Eczacılık Fakültesi Temel Eczacılık Bilimleri Bölümü Koleksiyonu
Recent Submissions
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Broccoli pomace: effect of drying methods and temperature on the grinding process and physicochemical properties
(Polska Akademia Nauk, 2024)The objective of this study was to evaluate the impact of different drying methods and temperatures on the physicochemical properties of broccoli pomace. The broccoli juice by-product was subjected to contact-drying at ... -
Investigation of Cuckoo-Pint's (Arum maculatum) phytochemistry, in vitro antioxidant potential, enzyme inhibition, and antimicrobial activity
(John Wiley and Sons Inc., 2024)Arum maculatum, cuckoo-pint in folk linguistics, is a poisonous but medicinal plant with tremendous properties that need investigation. This study subjected cuckoo-pint's parts to in vitro antioxidant, enzyme inhibition, ... -
The anticholinesterase perspective of dimethoxyindole based benzenesulfonamides: Synthesis, biological investigation and molecular docking applications
(John Wiley and Sons Inc., 2024)Due to the well-known biological potential of benzenesulfonamides for the inhibition of specific enzymes, here in, we propose to investigate anticholinesterase efficiencies of five newly synthesized benzenesulfonamides ... -
Environmentally friendly silver nanoparticles synthesized from Verbascum nudatum var. extract and evaluation of its versatile biological properties and dye degradation activity
(Springer, 2024)In the present study, green synthesis of silver nanoparticles (VNE-AgNPs) via Verbascum nudatum extract was carried out for the first time. The synthesized AgNPs were characterized by different spectral methods such as ... -
LC-MS /MS characterization and biological activities of Morina persica L. (Caprifoliaceae)
(Marmara University, 2024)The study aimed to comprehensively identify the phenolic fingerprint of Morina persica L. (Caprifoliaceae) and evaluate its various biological activities. LC-MS/MS analysis of 70% Morina persica methanol extract revealed ... -
Synthesis of furo[2,3-c]carbazoles as potent α-glucosidase and α-amylase inhibitors
(Taylor and Francis Ltd., 2024)The carbazole-3-carbaldehyde 2, produced by N-ethyl carbazole via Vilsmeier-Haack reaction, was subjected to Dakin type oxidation with H2O2 and H2SO4 in methanol to produce the carbazole-3-ol 3. The reaction of 3 with a ... -
Xanthine oxidase inhibitory activity and uric acid dissolution power of some plant extracts: In vitro therapeutical approach for gout treatment
(Springer Science and Business Media Deutschland GmbH, 2024)Elevated serum levels of uric acid are associated with an increased risk of hyperuricemia and gout. Recent attention has focused on the bioactive properties of plant extracts in preventing disease. Therefore, this study ... -
Anti-Cataract effect of the traditional aqueouse extract of yerba mate (Ilex paraguariensis A. St.-Hil.): An in ovo perspective
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Introduction: The therapeutic effect of different doses of the traditional aqueous extract of dried leaves of yerba mate (Ilex paraguariensis A. St.-Hil.) was investigated in an experimental cataract model in chicken ... -
Synthesis, biologic properties, and molecular modeling studies of bis-indole based thiosemicarbazones
(Springer, 2024)The Schiff base condensation reaction of thiosemicarbazides and methylene bridged 2,2′-bisindolylmethanes, prepared from the acid-catalyzed condensation of 3-aryl-4,6-dimethoxyindole-7-carbaldehydes and formaldehyde, ... -
Comprehensive phytochemical analysis of Salvia hispanica L. callus extracts using LC–MS/MS
(John Wiley and Sons Ltd, 2024)In this research, the study utilized the root, leaf, and petiole parts of in vitro grown Salvia hispanica plants as explants. Following UV-C treatment applied to developing callus, methanol extracts were obtained and ... -
Comparative chemical profiling and antioxidant properties of essential oils extracted from: Foeniculum vulgare subsp. piperitum (Ucria) Bég and Deverra scoparia Coss. & Durieu
(Elsevier Ltd, 2024)The current research investigates for the first time, the antioxidant activity and chemical composition of essential oils (EOs) extracted from several samples dried stems for Foeniculum vulgare subsp. piperitum (Ucria) Bég ... -
The uprisal of a lost endemic edible species, Micromeria cymuligera: Comprehensive elucidation of its biological activities and phytochemical composition
(Elsevier Ltd., 2024)Bioactive plant species are gaining scientific importance daily. New natural goods with added value are encouraged by the link between health, modern and traditional lifestyles. For about 145 years, Micromeria cymuligera, ... -
The methanol extract of Centaurea depressa M. Bieb. -Containing nanoemulsion formulation: In vitro characterization and scratch assay
(Editions de Sante, 2024)Centaurea depressa M. Bieb. is used in traditional medicine as wound healing, antidiabetic, antibacterial, antimalarial, antirheumatic, diuretic, antipyretic, antibacterial, tonic, astringent, choleretic. It is popularly ... -
Amelioration potential of synthetic oxime chemical cores against multiple sclerosis and Alzheimer's diseases: Evaluation in aspects of in silico and in vitro experiments
(Elsevier B.V., 2024)Alzheimer disease (AD) and multiple sclerosis (MS) are inflammatory neurological disorders. The main symptom of AD is dementia, and the main symptoms of MS are vertigo, sexual dysfunction, cognitive problems, and fatigue. ... -
Inhibition of Nε-(carboxymethyl)lysine and Nε-(carboxyethyl)lysine formation in air-fried beef tenderloins marinated with concentrated cranberry juice
(Elsevier Ltd., 2024)The aim of this study was to investigate the effect of marinating beef tenderloin with concentrated cranberry juice on the formation of Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL). In order to achieve ... -
Inhibitory effect of homemade hawthorn vinegar-based marinade on Nε-(carboxymethyl)lysine and Nε-(carboxyethyl)lysine formation in beef tenderloins
(Elsevier Ltd., 2024)In this study, the inhibitory effects of homemade hawthorn vinegar-based marinade on the formation of Nε-(carboxymethyl) lysine (CML) and Nε-(carboxyethyl) lysine (CEL) during the cooking of beef tenderloins investigated. ... -
Effects of Cypermethrin on Serum Biochemistry and Liver Histopathology of Anabas testudineus
(Islamic Azad University, 2024)Cypermethrin is one of the most commonly used pesticides. In this study, the effects of cypermethrin on serum biochemistry and liver histology of Anabas testudineus were investigated. The fish have been exposed to sub-lethal ... -
Development and in vitro characterization nanoemulsion containing the methanol extract of Hypericum linarioides for wound healing: In vitro scratch assay
(Elsevier B.V., 2024)It was aimed to develop and in vitro characterize the methanol extract of Hypericum linarioides (MHL)-containing nanoemulsion formulation (MHL-NEF) to heal the wound effectively. MHL-NEF was prepared and its droplet size, ... -
Indolyl imine compounds as multi-target agents; synthesis, antidiabetic, anticholinesterase, antioxidant activities and molecular modeling
(Elsevier B.V., 2024)A new range of indolyl imine system 3d-l has been successfully prepared from 4,6-dimethoxy-2,3-diphenyl-indole-7-carbaldehyde 2a and 4,6-dimethoxy-3-aryl-indole-7-carbaldehyde 2b-c via Schiff base reaction. The structure ... -
A Focused review on cognitive improvement by the genus Salvia L. (Sage)-from ethnopharmacology to clinical evidence
(Mdpi, 2023)Ethnopharmacology has been an important starting point in medical and pharmaceutical sciences for discovering drug candidates from natural sources. In this regard, the genus Salvia L., commonly known as sage, is one of the ...