Browsing by Author "Fırat, Mehmet"
Now showing items 1-17 of 17
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7-Acetoxyhorminone from Salvia multicaulis Vahl. as Promising Inhibitor of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase
Yiğitkan, Serkan; Ertaş, Abdulselam; Salmas, Ramin Ekhteiari; Fırat, Mehmet; Orhan, İlkay Erdoğan (MDPI, 2022)3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase is a key enzyme involved in cholesterol biosynthesis and one of the most important targets for the treatment of hy-percholesterolemia. A limited number of studies ... -
Bioguided isolation of secondary metabolites from Salvia cerino-pruinosa Rech. f. var. cerino-pruinosa
Ertaş, Abdulselam; Çakırca, Hatice; Yener, İsmail; Akdeniz, Mehmet; Fırat, Mehmet; Topçu, Gülaçtı; Kolak, Ufuk (ACG Publications, 2021)Abstract: In the current study, the ethanol extracts prepared from the aerial parts and roots of an endemic species, Salvia cerino-pruinosa Rech. f. var. cerino-pruinosa were fractionated on silica gel columns and tested for ... -
Biological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey
Akdeniz, Mehmet; Yener, İsmail; Ertaş, Abdulselam; Fırat, Mehmet; Reşitoğlu, Barış; Haşimi, Nesrin; Kandemir, Sevgi İrtegün; Yılmaz, Mustafa Abdullah; Demirköz, Aslı Barla; Kolak, Ufuk; Öksuz, Sevil (ACG Publications, 2021)Abstract: In this study, investigation on the essential oils and ethanol extracts of naturally grown and cultivated Satureja macrantha samples were reported. The essential oil, flavour and terpenoid-steroid-flavonoid ... -
Comprehensive study of all Gundelia L. taxa exists in the globe: An insight on LC-MS/MS based phytochemical investigation and bioactivity potential of 22 species
Tarhan, Abbas; Fırat, Mehmet; Topal, Giray (Elsevier Ltd, 2023)Species from the Gundelia genus are among the important main therapeutic herbs widely used in Middle Eastern nations' traditional medicine. The emphasis of the current investigation was on the bioactive phytochemicals and ... -
A comprehensive study on chemical and biological investigation of thymus brachychilus jalas: A rich source of ursolic and oleanolic acids
Akdeniz, Mehmet; Yiğitkan, Serkan; Yılmaz, Mustafa Abdullah; Yener, İsmail; Varhan Oral, Elif; Fırat, Mehmet; Orhan, İlkay Erdoğan (Taylor & Francis Inc, 2023)The significance of Thymus species in the scientific community is growing steadily due to their extensive utilization in traditional medicine, food industry, and pharmaceutical sector, owing to their abundance in essential ... -
A detailed chemical and biological investigation of twelve allium species from Eastern Anatolia with chemometric studies
İzol, Ebubekir; Temel, Hamdi; Yılmaz, Mustafa Abdullah; Yener, İsmail; Ölmez, Özge Tokul; Kaplaner, Erhan; Fırat, Mehmet; Ertaş, Abdülselam (Wiley-V C H Verlag Gmbh, 2021)Allium species are widely consumed as food all over the world. The phenolic profile of ethanol extracts of aerial parts and roots of 12 Allium species, collected from five different Eastern Anatolia regions, were studied ... -
Determination and comparison of metal analysis in the species belonging to different families by inductively coupled plasma-mass spectrometry (ICP-MS)
Umaz, Adil; Fırat, Mehmet; Aydın, Fırat; Ertaş, Abdulselam (2022)The consumption of plants and their use for medicinal purposes are increasing day by day. Therefore, knowing the plant contents is important for human health. In this study, metal contents of nineteen species belonging to ... -
Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)
Umaz, Adil; Aydın, Fırat; Ölmez, Özge Tokul; Fırat, Mehmet; Öztürk, Mehmet; Ertaş, Abdulselam; Aydın, Işıl (Marmara University, 2022)The importance of plants in folk medicine and scientific studies is increasing day by day. In this context, the plants pose a danger to human health when they are eaten by the public, consumed as herbal tea or used as ... -
Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC-MS: Source species for valuable compounds with drug or drug potential
Akdeniz, Mehmet; Yener, İsmail; Dinçel, Demet; Fırat, Mehmet; Değirmenci, Dilek Karataş; Ertaş, Abdulselam (Wiley, 2022)Public use of Salvia species and their importance in the scientific world is continually increasing. It is known that this use and the importance of Salvia species are mostly due to the terpenoid compounds that they contain. ... -
Development and validation of a novel LC-MS/MS method for the quantitation of 19 fingerprint phytochemicals in salvia species: A chemometric approach
Yılmaz, Mustafa Abdullah; Ertaş, Abdulselam; Yener, İsmail; Ölmez, Özge Tokul; Fırat, Mehmet; Temel, Hamdi (Oxford University Press, 2022)Being traditionally utilized mainly as appetizers and herbal teas as well as used to ease abdominal pains, colds and gastrointestinal issues, the genus Salvia L. has gained significant consideration owing to its remarkable ... -
Essential oil contents of Hypericum linarioides , H. helianthemoides, and H. lydium with their biological activities: Importance of Hypericum genus in the cosmeceutical and pharmaceutical industries
Akdeniz, Mehmet; Yener, İsmail; Ertaş, Abdülselam; Dincel, Demet; Fırat, Mehmet; Kocakaya, Şafak Özhan; Yigitkan, Serkan; Türkmenoğlu, Fatma Pınar; Aydın, Fırat; Kolak, Ufuk (Springer, 2023)In the literature, more than 3000 studies have been carried out on species in the Hypericum genus in the last ten years, especially for H. perforatum. The importance of Hypericum species in traditional medicine and modern ... -
Essential oil, aroma, and fatty acid profiles of five endemic Salvia taxa from Turkey with chemometric analysis
Ertaş, Abdulselam; Akdeniz, Mehmet; Yener, İsmail; Öztürk, Mehmet; Ölmez, Özge Tokul; Fırat, Mehmet; Kolak, Ufuk (Wiley-V C H Verlag GMBH, 2022)The essential oil, aroma, and fatty acid compositions of Salvia cerino-pruinosa var. cerino-pruinosa, S. cerino-pruinosa var. elazigensis, S. pseudeuphratica, S. rosifolia, and S. kurdica collected in 2015, 2016, and 2017 ... -
Güneydoğu Anadolu Bölgesinin Farklı Lokasyonlarından Toplanan Boynuzlu Geven (AstragalushamosusL.) Otunun Bazı Kalite Özelliklerinin Belirlenmesi
Bu çalışma, Güneydoğu Anadolu Bölgesinde yayılış gösteren AstragalushamosusL. türünün hayvanlar için besleme değerlerinintespit edilmesi ve lokasyonların benzerlik durumlarınınortaya çıkarılması amacıyla yürütülmüştür. ... -
An investigation and comparison of concentration change in simulated body fluid medium conditions of the calcium element in 27 different salvia species
Umaz, Adil; Aydın, Fırat; Fırat, Mehmet; Yener, İsmail; Ertaş, Abdülselam; Elmastaş, Ayhan (Istanbul University, 2023)Background and Aims: In this study, calcium (Ca) element concentration changes of Salvia species in simulated body fluid (SBF) medium conditions were investigated and the results in these medium conditions were compared ... -
Isolation of secondary metabolites of two endemic species: Salvia rosifolia Sm. and Salvia cerino-pruinosa Rech. f. var. elazigensis (Lamiaceae)
Yarış, Esra; Adsız, Leyla Balur; Yener, İsmail; Tuncay, Eyyüp; Yılmaz, Mustafa Abdullah; Akdeniz, Mehmet; Kaplaner, Erhan; Fırat, Mehmet; Ertaş, Abdulselam; Kolak, Ufuk (Springer, 2021)In the present study, activity-guided isolation and structural elucidation of antioxidant secondary metabolites of ethanol extracts prepared from the root and aerial parts of Salvia rosifolia and Salvia cerino-pruinosa ... -
Phytochemical fingerprints and bioactivities of ripe disseminules (Fruit-Seeds) of seventeen gundelia (Kenger-Kereng Dikeni) species from Anatolia with chemometric approach
Ertaş, Abdülselam; Fırat, Mehmet; Yener, İsmail; Akdeniz, Mehmet; Yiğitkan, Serkan; Bakır, Derya; Çakır, Cansel; Yılmaz, Mustafa Abdullah (Wiley-V C H Verlag Gmbh, 2021)Gundelia species are known as Kenger-kereng dikeni in Anatolia, and their aerial parts are consumed as food. Also, roots and seeds (disseminules) of the Gundelia species are used to prepare gum and coffee. The chemical ... -
Trace element analysis in some salvia species by inductively coupled plasma-mass spectrometry (Icp-ms) and chemometric approach
Tunay, Zeki; Yener, İsmail; Oral, Elif Varhan; Demirkoz, Aslı Barla; Ölmez, Özge Tokul; Fırat, Mehmet; Öztürk, Mehmet; Aydın, Işıl; Aydın, Fırat; Ertaş, Abdülselam (Marmara University, 2020)In this study, the stems, leaves, flowers, roots and mixed all parts of five Salvia species were analyzed for their trace element (Li, Be, V, Cr, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Ag, Cd, Cs, Ba, Hg, Tl, Pb, and U) contents ...
