Browsing by Author "Boǧa, Mehmet"
Now showing items 1-7 of 7
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The anticholinesterase perspective of dimethoxyindole based benzenesulfonamides: Synthesis, biological investigation and molecular docking applications
Bingül, Murat; Ercan, Selami; Boǧa, Mehmet; Arslan, Zehra; Tuneğ, Muhammed; Akocak, Süleyman; Bingül, Alev Arslantürk; Şengül, İbrahim Fazıl; Şahin, Hasan (John Wiley and Sons Inc., 2024)Due to the well-known biological potential of benzenesulfonamides for the inhibition of specific enzymes, here in, we propose to investigate anticholinesterase efficiencies of five newly synthesized benzenesulfonamides ... -
Antioxidant, acetylcholinesterase and butyrylcholinesterase inhibition profiles of histamine schiff bases
Akocak, Süleyman; Lolak, Nabih; Tuneğ, Muhammed; Boǧa, Mehmet (Turkish Chemical Society, 2019)In this work, a series of histamine Schiff bases H(1-20) were assayed for antioxidant properties by using different bioanalytical methods such as DPPH-free radical scavenging assay, ABTS cation radical decolarization, ... -
Indolyl imine compounds as multi-target agents; synthesis, antidiabetic, anticholinesterase, antioxidant activities and molecular modeling
Ceyhan, Sadık M.; Zengin, İrem Nur; Bingül, Murat; Şahin, Hasan; Boǧa, Mehmet; Sağlam, Mehmet F.; Kandemir, Hakan (Elsevier B.V., 2024)A new range of indolyl imine system 3d-l has been successfully prepared from 4,6-dimethoxy-2,3-diphenyl-indole-7-carbaldehyde 2a and 4,6-dimethoxy-3-aryl-indole-7-carbaldehyde 2b-c via Schiff base reaction. The structure ... -
Some heterocycles connected to substituted piperazine by 1,3,4-oxadiazole linker: Design, synthesis, anticholinesterase and antioxidant activity
Kurt, Zuhal Kılıç; Konyar, Dilan; Okur, Hayati; Kaplan, Alevcan; Boǧa, Mehmet (Elsevier B.V., 2025)AD is a multifactorial neurodegenerative disease that has caused morbidity and mortality on a global scale. Currently, there are only a few drugs used in the treatment of AD. Although many compounds that aim at new targets ... -
Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile
Lolak, Nabih; Boǧa, Mehmet; Tuneğ, Muhammed; Karakoç, Gulçin; Akocak, Suleyman; Supuran, Claudiu T. (Taylor and Francis Ltd, 2020)A series of 16 novel benzenesulfonamides incorporating 1,3,5-triazine moieties substituted with aromatic amines, dimethylamine, morpholine and piperidine were investigated. These compounds were assayed for antioxidant ... -
Synthesis of novel N-Acylhydrazones derived from 3,5-dinitrobenzohydrazide and evaluation of their anticholinesterase and antioxidant activities
Çakmak, Reşit; Çınar, Ercan; Başaran, Eyüp; Tuneğ, Gülsüm; İzgi, Sevcan; Boǧa, Mehmet (Pleiades Publishing, 2024)Abstract: Objective: In this study, it was aimed to determine the antioxidant activities and enzyme inhibition properties of newly synthesized N-acylhydrazone compounds (IIIa–IIIp) bearing an aryl sulfonate moiety. Methods: ... -
Synthesis, biologic properties, and molecular modeling studies of bis-indole based thiosemicarbazones
Ceyhan, Sadık M.; Bingül, Murat; Şahin, Hasan; Boǧa, Mehmet; Sağlam, Mehmet F.; Kandemir, Hakan; Şengül, İbrahim Fazıl (Springer, 2024)The Schiff base condensation reaction of thiosemicarbazides and methylene bridged 2,2′-bisindolylmethanes, prepared from the acid-catalyzed condensation of 3-aryl-4,6-dimethoxyindole-7-carbaldehydes and formaldehyde, ...
