Browsing by Author "Bilgin, Hakki Murat"
Now showing items 1-12 of 12
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Antiepileptic effects of ghrelin on pentylenetetrazole-induced seizures in rats
Obay, Basra Deniz; Tasdemir, Ezel; Tuemer, Cemil; Bilgin, Hakki Murat; Sermet, Abdurrahman (Elsevier Science Inc, 2007)It is well known that neuropeptide Y (NPY) and gamma-aminobutyric acid (GABA) exert antiepileptic effects in animal models. It has recently been shown that ghrelin neurons increase the activities of GABA and NPY in the ... -
Comparison of the anti-diabetic effects of resveratrol, gliclazide and losartan in streptozotocin-induced experimental diabetes
Yazgan, Umit Can; Tasdemir, Ezel; Bilgin, Hakki Murat; Obay, Basra Deniz; Sermet, Abdurrahman; Elbey, Bilal (Taylor & Francis Ltd, 2015)Aim: The aim of this study was to compare the effect of the resveratrol with gliclazide and losartan in streptozotocin induced diabetic rats. Materials and methods: Adult male Wistar albino rats were divided into five ... -
Comparison of the effect of local microvibration and pulsed electromagnetic field application on bone fracture
Bilgin, Hakki Murat; Celik, Ferhat; Akpolat, Veysi; Yildiz, Ismail; Ekinci, Aysun; Gem, Mehmet (Wiley-Blackwell, 2015)[Abstract Not Available] -
Dose dependent effects of ghrelin on pentylenetetrazole-induced oxidative stress in a rat seizure model
Obay, Basra Deniz; Tasdemir, Ezel; Tuemer, Cemil; Bilgin, Hakki Murat; Atmaca, Mukadder (Elsevier Science Inc, 2008)It has been suggested that free oxygen radicals play a role in the genesis of epilepsy and in post-seizure neuronal death. The aim of this study was to investigate the dose dependent effect of ghrelin on pentylenetetrazole ... -
Effect of 900-, 1800-, and 2100-MHz radiofrequency radiation on DNA and oxidative stress in brain
Alkis, Mehmet Esref; Bilgin, Hakki Murat; Akpolat, Veysi; Dasdag, Suleyman; Yegin, Korkut; Yavas, Mehmet Cihan; Akdag, Mehmet Zulkuf (Taylor & Francis Inc, 2019)Ubiquitous and ever increasing use of mobile phones led to the growing concern about the effects of radiofrequency radiation (RFR) emitted by cell phones on biological systems. The aim of this study is to explore whether ... -
Effect of ghrelin administration on phagocytic activity in acute cold-restraint stress exposed rats
Tumer, Cemil; Bilgin, Hakki Murat; Obay, Basra Deniz; Diken, Huda; Tasdemir, Ezel; Sermet, Abdurrahman (Elsevier, 2007)Ghrelin, an endogenous ligand for growth hormone secretagogue receptor, was identified in the rat stomach. This peptide acts through nitric oxide (NO) by expressing endothelial nitric oxide synthase (eNOS) and down regulating ... -
Effect of nitric oxide on phagocytic activity of lipopolysaccharide-induced macrophages
Tumer, Cemil; Bilgin, Hakki Murat; Obay, Basra Deniz; Diken, Huda; Atmaca, Mukadder; Kelle, Mustafa (Wiley, 2007)Among the antimicrobial mechanisms associated with macrophages, NO produced by iNOS plays a major role in intracellular killing, but the relationship between NO and phagocytic activity after injection of inflammatory agents ... -
Effects of increasing ratio of progesterone in estrogen/progesterone combination on total oxidant/antioxidant status in rat uterus and plasma
Hekimoglu, Askin; Bilgin, Hakki Murat; Kurcer, Zehra; Ocak, Ali Riza (Springer Heidelberg, 2010)The relationship between increasing ratio of progesterone in estrogen/progesterone combination and oxidative stress (OS) was investigated. Thirty non-pregnant Wistar Albino female rats were divided into five groups and ... -
The hepatoprotective effect of coumarin and coumarin derivates on carbon tetrachloride-induced hepatic injury by antioxidative activities in rats
Atmaca, Mukadder; Bilgin, Hakki Murat; Obay, Basra Deniz; Diken, Huda; Kelle, Mustafa; Kale, Ebru (Springer, 2011)Coumarins are a vast group of natural compounds and some of them possess antioxidant activities. The comparison of the antioxidant activity of some coumarins with various chemical molecular structure has not been investigated ... -
Influence of coumarin and some coumarin derivatives on serum lipid profiles in carbontetrachloride-exposed rats
Tasdemir, Ezel; Atmaca, Mukadder; Yildirim, Yasar; Bilgin, Hakki Murat; Demirtas, Berjan; Obay, Basra Deniz; Kelle, Mustafa (Sage Publications Ltd, 2017)In the present study, coumarin and some coumarin derivatives (esculetin, scoparone, and 4-methylumbelliferone) were investigated for their lipid-lowering effect in rats. Male Sprague-Dawley rats (150-200 g) were divided ... -
Investigation of the effects of pulsed electromagnetic fields and calcium-channel blockers on osteogenesis
Bilgin, Hakki Murat; Agacayak, Serkan; Akpolat, Veysi; Yildiz, Ismail (Wiley-Blackwell, 2016)[Abstract Not Available] -
Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats
Bilgin, Hakki Murat; Atmaca, Mukadder; Obay, Basra Deniz; Ozekinci, Selver; Tasdemir, Ezel; Ketani, Aydin (Elsevier Gmbh, Urban & Fischer Verlag, 2011)The comparison of the antioxidant activity of some coumarins with their molecular structure is well determined. However, the protective function of coumarins with various chemical structures against liver toxicity has not ...