Browsing by Author "Hitit, Mustafa"
Now showing items 1-13 of 13
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Alcoholic extract of Tarantula cubensis induces apoptosis in MCF-7 cell line.
Er, Ayse; Corum, Orhan; Corum, Duygu; Hitit, Mustafa; Donmez, Huseyin; Guzeloglu, Aydin (Allied Acad, 2017)Tarantula cubensis Alcoholic Extract (TCAE) is a homeopathic agent used for treating many disorders. This study aimed to define the effects of TCAE on the breast carcinoma cell line (MCF-7). After various concentrations ... -
Altered luteal expression patterns of genomic and non-genomic progesterone receptors in bitches at different reproductive states
Uçar, Eyyüp Hakan; Peker, Cevdet; Hitit, Mustafa; Köse, Mehmet; Tatar, Musa; Bozkaya, Faruk; Atlı, Mehmet Osman (Elsevier Inc., 2024)The binding of steroid hormones to their specific receptors is necessary to exert their effects on target cells. Progesterone (P4), a steroid hormone, carries out its effects through both genomic and non-genomic (the cell ... -
Cell-specific expression pattern of toll-like receptors and their roles in animal reproduction
Atlı, Mehmet Osman; Hitit, Mustafa; Özbek, Mehmet; Köse, Mehmet; Bozkaya, Faruk (Springer Science and Business Media Deutschland GmbH, 2022)Toll-like receptors (TLRs), a part of the innate immune system, have critical roles in protection against infections and involve in basic pathology and physiology. Secreted molecules from the body or pathogens could be a ... -
Circulating miRNAs in maternal plasma as potential biomarkers of early pregnancy in sheep
Hitit, Mustafa; Kose, Mehmet; Kaya, Mehmet Salih; Kirbas, Mesut; Dursun, Sukru; Alak, Ilyas; Atli, Mehmet Osman (Frontiers Media Sa, 2022)MicroRNA (miRNA) plays an important role in the control of gene expression and is implied in many biological functions, including embryo implantation and development. The aim was to assess plasma miRNA profiles during the ... -
Effects of essential oil mixtures on expression of genes involved in lipogenesis and fatty acid oxidation in geese (Anser anser)
Aydın, Özlem Durna; Hitit, Mustafa; Usta, Zafer; Yıldız, Gültekin; Saçaklı, Pınar; Kaplan, Oktay; Merhan, Oğuz (Springer Science and Business Media B.V., 2024)The use of essential oils has recently increased in the poultry sector. The aim of this study was to investigate the effects of essential oil mixture (juniper, mint, oregano and rosemary oil) on fatty acid oxidation and ... -
Expression of circulating oar-miR-485-5p and oar-miR-493-5p during the estrous cycle and early pregnancy in ovine plasma
Ucar, Eyyup Hakan; Hitit, Mustafa; Kose, Mehmet; Atli, Mehmet Osman (Brazilian Coll Animal Reproduction, 2024)In the current study, we aimed to assess the expression levels of two circulating microRNAs (miRNA) (oar-miR-485-5p and oar-miR-493-5p) in the ovine plasma during the peri-implantation. After mating, we collected the plasma ... -
Expression pattern and cellular localization of two critical non-nuclear progesterone receptors in the ovine corpus luteum during the estrous cycle and early pregnancy
Atli, Mehmet O.; Akbalik, Mehmet Erdem; Kose, Mehmet; Alak, Ilyas; Atli, Zehra; Hitit, Mustafa (Elsevier, 2022)The study aimed to investigate the expression and cellular localization of two critical non-nuclear progesterone receptors, including membrane-associated-progesterone-receptor-component-1 (PGRMC1) and progestin and adipoQ ... -
Expression pattern of microRNAs in ovine endometrium during the peri-implantation
Kose, Mehmet; Hitit, Mustafa; Kaya, Mehmet Salih; Kirbas, Mesut; Dursun, Sukru; Alak, Ilyas; Atli, Mehmet Osman (Elsevier Science Inc, 2022)MicroRNA (miRNA), acting as the transcriptional regulator of gene expression, has been widely demonstrated to be involved in many biological functions, including embryo implantation and devel-opment. The objective of the ... -
Expression patterns of genes in steroidogenic, cholesterol uptake, and liver x receptor-mediated cholesterol efflux pathway regulating cholesterol homeostasis in natural and PGF2? induced luteolysis as well as early pregnancy in ovine corpus luteum
Hitit, Mustafa; Kose, Mehmet; Kocak, Nadir; Atli, Mehmet Osman (Elsevier, 2022)The aim was to evaluate the expression of genes of steroidogenic, cholesterol uptake, and liver X receptor (LXR) mediated cholesterol efflux pathway in ovine corpus luteum (CL) during natural and prostaglandin F2 alpha ... -
Expression patterns of Toll-like receptors in the ovine corpus luteum during the early pregnancy and prostaglandin F2?-induced luteolysis
Atli, Mehmet O.; Kose, Mehmet; Hitit, Mustafa; Kaya, M. Salih; Bozkaya, Faruk (Elsevier Science Inc, 2018)The aim of this study was to elucidate the expression profiles of Toll-like receptors (TLRs) in the ovine corpus luteum (CL) during early pregnancy and prostaglandin F2 alpha (PGF2 alpha)-induced luteolysis. For this ... -
Investigation of interferon-tau stimulated genes (ISGs) simultaneously in the endometrium, corpus luteum (CL) and peripheral blood leukocytes (PBLs) in the preluteolytic stage of early pregnancy in ewes
Kiyma, Zekeriya; Kose, Mehmet; Atli, Mehmet Osman; Ozel, Caglayan; Hitit, Mustafa; Sen, Gonca; Kaya, Muhammet (Elsevier, 2016)The aim of the present study was to investigate the expression profiles of Interferon-tau (IFN-T) stimulated genes (ISGs) at the mid-luteal stage of the cycle (on day 13) in the uterine endometrium and extra-uterine tissues, ... -
Kısrak endometriyumunda Phosphatase and Tensin Homolog (PTEN) geni mRNA ekspresyonunun araştırılması
Kayış, Seyit Ali; Güzeloğlu, Aydın; Şen, Gonca; Hitit, Mustafa; Atlı, Mehmet Osman; Kurar, Ercan; Özel, Çağlayan (2015)Amaç: Bu çalışmanın amacı, siklüs ve erken gebelik dönemlerinde dinamik bir yapıya sahip olan kısrak endometriyumunda phosphatase and tensin homolog (PTEN) gen ekspresyonunun mRNA düzeyinde belirlenmesidir.Gereç ve Yöntem: ... -
Relative abundance and localization of interferon-stimulated gene 15 mRNA transcript in intra- and extra-uterine tissues during the early stages of pregnancy in sheep
Alak, Ilyas; Hitit, Mustafa; Kose, Mehmet; Kaya, M. Salih; Ucar, Eyyup Hakan; Atli, Zehra; Atli, Mehmet O. (Elsevier, 2020)The aim of this study was to investigate relative abundance and localization of ISG15 mRNA transcript in intra-uterine (trophoblast, endometrium) and extra-uterine (hypothalamus, anterior pituitary, corpus luteum) tissues ...
