Taşkesen M.Yarami?s A.Gözü Pirinççioğlu A.Devecioğlu C.2024-04-242024-04-2420121300-0381https://hdl.handle.net/11468/24902Pyridoxine-dependent seizures, characterized by various intractable seizure types, usually occur during the first hours of life. Typically, pyridoxine-dependent seizures are unresponsive to anticonvulsant drugs and they respond only to immediate administration of pyridoxine hydrochloride. We have reported a 5-day-old boy who was presented with flexor type tonic spasms with clustering beginning in the first hours of his life. The spasms were refractory to several anticonvulsant drugs but they responded well to pyridoxine treatment. This report emphasizes the importance of considering pyridoxine-dependent epileptic encephalopathy in newborn babies who are unresponsive to anticonvulsant drugs. Copyright © 2012 by Türkiye Klinikleri.eninfo:eu-repo/semantics/closedAccessEpilepsyInfant, NewbornVitamin B6 DeficiencyArticle2131861882-s2.0-84868093899Q4