Erdoğan, ÖmerTopal, Giray2025-03-082025-03-0820152618-6136https://doi.org/10.23884/mejs.2015.1.2.02https://hdl.handle.net/11468/31748Enantiomer separation has attracted increasing attentions in pharmaceutical industry, due to great differences in pharmacological, toxicological and/or metabolic activities of enantiomeric drugs in living system. Several methods have been succesfully used to achieve chiral separation. To date the chromatographic method is one of the most effective. Numerous kinds of CSPs have been developed for chiral separation these include cyclo-dextrins, polysaccharides, macrocyclic antibiotics, ligand-exchange, Pirkle, crown ethers and protein derivatives. İn this rewiev we will inform ligands and macromolecules used as CSP.eninfo:eu-repo/semantics/openAccessenantiomeric separationchiral stationary phasesArticle12284110.23884/mejs.2015.1.2.02