Oruc, ZeynepKaplan, Mehmet AliUrakci, ZuhatKucukoner, MehmetAvci, YahyaIsikdogan, Abdurrahman2024-04-242024-04-2420151300-7467https://doi.org/10.5505/tjoncol.2015.1168https://hdl.handle.net/11468/20170Achantosis Nigricans (AN) is a skin disorder characterised with hyperpigmented hyperkeratotic lesions. It occurs mostly in association with insulin resistance while it may also arise as a symptom of visceral malignancies. In the occurrence of AN considered as associated with malignancy, a detailed examination may be necessary to identify underlying malignancy. 85% of malign AN cases abdominal adenocarcinomas, and especially 60% of those are gastric adenocarcinomas. A 44-year-old male patient applied to our clinic with hyperpigmentation and hyperkeratosis, widespread body pain and weight loss within 3-4 months. Skin symptoms were reviewed as acanthosis nigricans. He had no endocrinological diseases such as DM or obesity. Due to ocurrence of many skin symptoms in accordance with acanthosis nigricans in a rapid growth on our patient, no findings of other AN causes, systemic symptoms such as the age of patient and weight loss, it is considered as malign AN.trinfo:eu-repo/semantics/openAccessAcanthosis NigricansArticle303140143WOS:0003793603000042-s2.0-8494487751110.5505/tjoncol.2015.1168Q4N/A