Aydin, HÖzdemir, NUzunören, N2024-04-242024-04-2420050379-0738https://doi.org/10.1016/j.forsciint.2005.04.018https://hdl.handle.net/11468/15433Joint Meeting of the Society-of-Forensic-Toxicologists/International-Association-of-Forensic-Toxicologists -- AUG 30-SEP 03, 2004 -- Washington, DCThe accumulation of 2,4-dichlorophenoxyacetic acid (2,4-D) and its metabolite 2,4-dichlorophenol (2,4-DCP) in the kidneys of rats was investigated. Male and female Sprague-Dawley rats were given 2,4-D in drinking water and food for 30 days. Group A (control group) was fed a normal diet, Group B Was fed 50 ppm 2,4-D in 15 g food, Group C received 100 ppm 2,4-D in 15 g food, Group D received 25 ppm 2,4-D in 15 ml drinking water and Group E was given 50 ppm 2,4-D in 15 ml of drinking water. Levels of 2,4-D and 2,4-DCP in kidneys were determined using high performance liquid chromatography (HPLC). It was observed that at low doses of 2,4-D, the metabolite, 2,4-DCP found in the kidneys. (C) 2005 Elsevier Ireland Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccess2,4-Dichlorophenoxyacetic Acid (2,4-D)2,4-Dichlorophenol (2,4-Dcp)HplcKidney AccumulationRatConference Object15315357WOS:0002313042000092-s2.0-224444342601593558310.1016/j.forsciint.2005.04.018Q1Q1