Aǧaçayak, Kamil SerkanGüler, RıdvanIlyasov, Bekir2021-09-292021-09-292019Aǧaçayak, K. S., Güler, R. ve Ilyasov, B. (2019). Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography. Drug Design, Development and Therapy, 13, 3477-3484.1177-8881https://www.dovepress.com/evaluation-of-the-effect-of-long-term-use-of-antidepressants-in-the-ss-peer-reviewed-fulltext-article-DDDThttps://hdl.handle.net/11468/7812PMID:31631972Aim: The present study aims to employ dental volumetric tomography to examine bone mineral density among men that used antidepressants in the SSRI group for a long time. Method: The present study was conducted through the utilisation of data related to patients that presented to the Faculty of Dentistry of Dicle University and had a dental volumetric tomography (DVT) scan for any reason. The patients were divided into 2 groups based on the use of antidepressants: Group 1 included 68 patients as the control group, and Group 2 consisted of 68 patients that used antidepressants. Radiomorphometric measurements were performed on DVT data: DVT-Mandibular Index (DVT-MI), DVT-Cortical Index (DVT-CI), Hounsfıeld Unit (HU) CORTICAL, and HU SPONGIOSIS values were calculated. Results: The group of patients that used antidepressants exhibited a significant increase in DVT CI and a significant decrease in HU CORTICAL, HU SPONGIOSIS and DVT MI values. These findings were suggestive of osteoporosis. Conclusion: Long-term use of antidepressants should be taken into consideration as a risk factor for osteoporosis in men.eninfo:eu-repo/semantics/openAccessAntidepressantBone densityDental tomographyArticle1334773484WOS:0004891635000022-s2.0-850735064593163197210.2147/DDDT.S216822Q1Q2