Güneş, AhmetGül, ÖzlemAkın, AlperTüre, MehmetBalık, HasanBilici, Meki2022-08-262022-08-262022Güneş, A., Gül, Ö., Akın, A., Türe, M., Balık, H. ve Bilici, M. (2022). Evaluation of children with acute rheumatic fever: A single-center experience. Turkish Archives of Pediatrics, 57(1), 26-31.2757-6256https://search.trdizin.gov.tr/yayin/detay/529132https://hdl.handle.net/11468/10258https://search.trdizin.gov.tr/yayin/detay/529132Objective: The epidemiological characteristics, risk factors, complications, recurrence status, clinical and laboratory features, and treatment methods of the patients who admitted to our Pediatric Cardiology Outpatient Clinic with a pre-diagnosis of acute rheumatic fever (ARF) were evaluated. Materials and Methods: The data of 166 patients who admitted with a pre-diagnosis of ARF and were diagnosed with ARF, and the data of 51 patients who were not diagnosed with ARF, were retrospectively analyzed. Results: The patients with ARF were between the ages of 5 and 18. Most of the patients with ARF attack admitted in December (15.6%), January (13.8%), and February (13.2%). The most common complaints of the patients diagnosed with ARF were isolated joint pain and/or swelling, at 50.6%. While 91.5% of the patients were diagnosed for the first time, 8.5% had ARF recurrence. It was seen that the most common major criterion was carditis (94.6%). The severity of valve regurgitation and the rates of monoarthritis were significantly higher in patients with recurrence (P < .05). Non-compliance with prophylaxis was observed in 10 (71.4%) of 14 patients with recurrence, and in 43 (28.2%) of 152 patients without recurrence. Anti-streptolysin O was lower (P = .021) and alanine transaminase (ALT) was higher (P = .019) in the recurrence group. Conclusion: Our study showed that in patients with a pre-diagnosis of ARF, a differential diagnosis should be made with other diseases. Especially in patients with joint complaints as the only major symptom, a differential diagnosis should be made. ARF recurrence is associated with non-compliance with prophylaxis, and both the severity of valve regurgitation and monoarthritis rates are higher in patients who develop recurrence. Alanine aminotransferase is significantly higher in patients with ARF recurrence.eninfo:eu-repo/semantics/openAccessAcute rheumatic feverCarditisArthritisRecinceArticle5712631WOS:0007440601000052-s2.0-851249978245291323511007510.5152/TurkArchPediatr.2021.21064Q3N/A