Aydogdu, BahattinAzizoglu, MustafaArslan, SerkanAydogdu, GulayBasuguy, ErolSalik, FikretOkten, Mustafa2024-04-242024-04-2420230016-3813https://doi.org/10.24875/GMM.M22000750https://hdl.handle.net/11468/18974Background: Acute appendicitis diagnosis can sometimes be a real challenge in pediatric patients. Objective: To establish the importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and other hematological parameters adjusted for age and sex in the prediction of acute appendicitis, as well as to describe a new scoring system. Material and methods: Medical records of 946 children hospitalized for acute appendicitis were retrospectively analyzed. A scoring system based on NLR, PLR, lymphocyte/monocyte ratio (LMR), and C-reactive protein (CRP) adjusted for age and sex was developed. Results: Patients were divided into group I, with negative examination, and group II, with acute appendiand PCR were higher in group II. The scores ranged from 0 to 8 points; 4.5 was determined to be the best cut-off point for acute appendicitis with the highest area under the curve (0.96), sensitivity (94%), specificity (86%), positive predictive value (97.5%), negative predictive value (65%), accuracy (92.6%) and misclassification rate (7.4%). Conclusion: The proposed scoring system, calculated based on patient age and gender, can be used for unnecessary surgeries to be avoided.eninfo:eu-repo/semantics/openAccessPediatric AppendicitisAdjusted Neutrophil-Lymphocyte RatioNovel Scoring SystemArticle1592106112WOS:00096206300000510.24875/GMM.M22000750N/A