Ozdemir, Hasan HuseyinDemiroren, KaanDemir, Caner F.Serin, Mine Hapsen2024-04-242024-04-2420140004-282X1678-4227https://doi.org/10.1590/0004-282X20140099https://hdl.handle.net/11468/18610P300 event-related potentials (ERPs), objective measures related to cognitive processing, have not been studied in Sydenham's chorea (SC) patients. Purpose: To assess cognitive impairment with P300 ERPs. Method: Seventeen patients with SC and 20 unaffected healthy children were included. Stanford-Binet test was used for psychometric assessment, and odd-ball paradigm was used for auditory ERPs. Results: There was no significant difference in P300 latencies between the SC-pretreatment group, SC-posttreatment group and control group (p>0.05). Mean interpeak latencies in SC-pretreatment group and SC-posttreatment group showed significant prolongation compared with the control group (p<0.05). Mean interpeak latencies in SC-posttreatment group were significantly decreased compared with SC-pretreatment group (p<0.05). Compared to controls, patients did not show significant difference in Stanford-Binet intelligence examination. Conclusion: This report suggests that interpeak latencies and amplitudes of P300 ERPs could be useful for detecting and monitoring cognitive impairment in SC patients.eninfo:eu-repo/semantics/openAccessSydenham's ChoreaCognitive FunctionEvent-Related PotentialsArticle728603608WOS:0003412794000082-s2.0-849056493562509847710.1590/0004-282X20140099Q3Q4