Turhanoglu S.Ozyilmaz M.A.Tok D.Olmez G.Bayhan N.2024-04-242024-04-2419991016-5150https://hdl.handle.net/11468/24124The effects of ondansetron on postoperative nausea and vomiting (PONV) were investigated in laparoscopic gynecologic procedures and 120 patients were included to the study. Ondansetron 4 mg was administered via intravenous route to group I (n=30) immediately before induction, to group II (n=30) fifteen minutes before ending of surgery and also to group III (n=30) one hour before anaesthesia induction via oral route. Any drugs weren't given for preventing PONV to group IV (n=30) and was accepted as a control group. The patients were followed postoperatively in three periods as 0-2, 2-6 and 6-24 hours to assess PONV. Metoclopramide 10 mg was administered IV to the patients if necessary. Incidence of nausea were significantly lower in the patients of group I at the second and third periods (p<0.05). The incidence of vomiting were seen significantly low in the patients of groups I and II during the first period and vomiting were not present in the first group during the second and third periods (p<0.05). We concluded that the incidence of PONV could be decreased by using IV ondansetron 4 mg immediately before anesthesia induction or at the end of surgery in laparoscopic gynecologic procedures.trinfo:eu-repo/semantics/closedAccessAdministration TimeIntravenousOndansetronOralPostoperative Nausea And VomitingArticle2773683712-s2.0-0032742706N/A