Tok D.Turhanoglu S.Ozyilmaz M.A.Ozyurek L.Atasever J.2024-04-242024-04-2419941300-0012https://hdl.handle.net/11468/24568The efficacy of preincisional and postincisional infiltration with 0.025 % bupivacaine (40 ml) on the postoperative pain was evaluated in 60 adult (ASA I-II) patients undergoing for elective cholecystectomy. The patients were allocated randomly to receive infiltration of the surgical area with bupivacaine either 15 min. before skin incision (preincisional group) or immediately before skin closure (postincisional group). Local anesthetic infiltration was not administered to control group. The difference in time to first request for analgesic drug was compared between 3 groups. This period was found 511.5 ± 136.81 minutes for preincisional group, 343.25 ± 101.65 minutes for postincisional group and 257.5 ± 85.15 minutes for control group. We concluded that preincisional bupivacaine infiltration delayed the first analgesic requirement in the postoperative period.trinfo:eu-repo/semantics/closedAccessBupivacainePostoperative AnalgesiaArticle6327322-s2.0-0028003627Q3