Akbulut, HuseyinYavuz, MuratGuler, EmineDemirkol, Dilek OdaciEndo, TakeshiYamada, ShuheiTimur, Suna2024-04-242024-04-2420141759-99541759-9962https://doi.org/10.1039/c4py00079jhttps://hdl.handle.net/11468/16468A simple and efficient approach for the electrochemical deposition of polypeptides as bio-based covering materials for surface design is described. The method involves N-carboxyanhydride (NCA) ring-opening polymerization from its precursor to form a thiophene-functionalized polypeptide macromonomer (T-Pala), followed by electropolymerization. The obtained conducting polymer, namely polythiophene-g- polyalanine (PT-Pala), was characterized and utilized as a matrix for biomolecule attachment. The biosensing applicability of PT-Pala was also investigated by using glucose oxidase (GOx) as a model enzyme to detect glucose. The designed biosensor showed a very good linearity for 0.01-1.0 mM glucose. Finally, the antimicrobial activities of newly synthesized T-Pala and PT-Pala were also evaluated by using the disc diffusion method.eninfo:eu-repo/semantics/closedAccess[No Keyword]Article51239293936WOS:0003368048000242-s2.0-8490130670010.1039/c4py00079jQ1Q1