Aşır, FıratKorak, TuğcanÖztürk, Özgür2023-03-172023-03-172021Aşır, F., Korak, T. ve Öztürk, Ö. (2021). Three MSA tools analysis in DNA and protein datasets. Middle East Journal of Science, 7(2), 89-99.2618-6136https://search.trdizin.gov.tr/tr/yayin/detay/507485https://hdl.handle.net/11468/11438https://search.trdizin.gov.tr/yayin/detay/507485Multiple sequence alignment (MSA) is the alignment of three or more sequences of DNA,RNA, and protein. MSA is used to construct phylogenetic trees and to compare evolutionaryrelationships between sequences analyzing similarities and dissimilarities. A variety of multiplesequence alignment tools are available, each using different methods and parameters to alignsequences. In this article three MSA tools; CLUSTALW, SAGA, and MAFFT were used to analyze fivedatasets BALiBASE_R9, DIRMBASE, SABmark, DNABali, and ProteinBali. The results showed that MAFFT may be more useful to align DNA and protein sequences than the other two tools.eninfo:eu-repo/semantics/openAccessMultiple sequence alignmentMAFFTSAGACLUSTALWArticle72899950748510.51477/mejs.983750