Güzel, TuncayBilik, Mehmet ZihniArslan, BayramKılıç, RaifAktan, Adem2022-06-172022-06-172021Güzel, T., Bilik, M. Z., Arslan, B., Kılıç, R. ve Aktan, A. (2021). The effect of atherogenic plasma index on collateral development in patients with chronic coronary total occlusion. Experimental Biomedical Research, 4(4), 291-301.2618-6454https://app.trdizin.gov.tr/makale/TkRnNU1UTTVPUT09https://hdl.handle.net/11468/10021https://search.trdizin.gov.tr/yayin/detay/489139Aim: To demonstrate the correlation between coronary collateral circulation (CCC) and atherogenic plasma index (AIP), one of the factors associated with the formation of collateral vessels. Methods: Hospital records of patients with chronic total occlusion (100% stenosis) in at least one coronary artery were evaluated. Triglycerides, HDL level, triglyceride/HDL ratio and atherogenic plasma index before coronary angiography were assessed for the 451 patients who met the study criteria. Results: Comparison of the two groups in terms of laboratory findings showed that triglyceride/HDL ratio (5.04±3.13 vs 3.56±2.12, p<0.001) and AIP (0.63±0.25 vs 0.48±0.25, p<0.001) were higher with statistical significance in the weak collateral group. The ROC analysis revealed an association between weak collateral formation and atherogenic plasma index with 64.7% sensitivity and 66.2% specificity using a cut-off value of 0.58 for AIP. Accordingly, low AIP was found to be an independent predictor of good collateral artery formation. Conclusion: This study suggests that a high atherogenic plasma index may be an independent factor associated with poor collateral formation.eninfo:eu-repo/semantics/openAccessCoronary arteryOcclusionCollateral vesselsAtherogenic plasma indexTriglyceride/HDL ratioArticle4429130148913910.30714/j-ebr.2021471924