Tuzcu, Sadiye AltunPekkolay, ZaferKilinc, FarukTuzcu, Alpaslan Kemal2024-04-242024-04-2420170091-49161535-5675https://doi.org/10.2967/jnmt.117.192708https://hdl.handle.net/11468/19017Insulinomas are the most common cause of hypoglycemia, resulting from endogenous hyperinsulinism. The diagnosis of insulinoma is established by demonstrating inappropriately high serum insulin concentrations during a spontaneous or induced episode of hypoglycemia. Most insulinomas are islet-cell tumors. They are often small (<2 cm), benign, and difficult to localize with current imaging techniques. Insulinomas can be detected using either noninvasive procedures (e.g., transabdominal ultrasonography, spiral CT, MRI, In-111-pentetreotide imaging, and F-18-L-dihydroxyphenylalanine PET) or invasive procedures (e.g., endoscopic ultrasonography) or a selective arterial calcium stimulation test with hepatic venous sampling. Methods: We performed Ga-68-DOTATATE PET/CT on 3 patients with insulinoma. Results: All patients' insulinomas were shown clearly with Ga-68-DOTATATE PET/CT. Conclusion: Ga-68-DOTATATE PET/CT imaging may be a useful noninvasive imaging technique to localize insulinomas preoperatively.eninfo:eu-repo/semantics/openAccessGa-68-Dotatate Pet/CtInsulinomaNeuroendocrine TumorArticle453198200WOS:0004168420000072-s2.0-850288717722879822710.2967/jnmt.117.192708Q3N/A