Bozbay, NizamettinBozbay, Özlem PolatAğaçayak, ElifOğlak, Süleyman CemilAvcı, FazılAcar, Abdullah2024-04-242024-04-242023Bozbay, N., Bozbay, Ö. P., Ağaçayak, E., Oğlak, S. C., Avcı, F. ve Acar, A. (2023). Prediction of posterior reversible encephalopathy syndrome (PRES) due to obstetric causes. Perinatal Journal, 31(3), 178-185.1305-3124https://doi.org/10.59215/prn.23.0313001https://hdl.handle.net/11468/23953Objective: This study aimed to identify the demographic, laboratory, and clinical parameters that would help us identify patients at risk of posterior reversible encephalopathy syndrome (PRES) due to obstetric causes. Also, we analyzed the variables that might predict the development of obstetric-related PRES. Methods: This retrospective study examined a total of 274 hypertensive pregnant women diagnosed with preeclampsia (PE) and eclampsia from January 2010 to December 2017 at Dicle University Faculty of Medicine. Of these, 85 cases who underwent cranial imaging by mag-netic resonance imaging (MRI) or computed tomography (CT) were included in the study. Results: According to the cranial imaging results, 48 patients (56.47%) were reported as PRES (Group 1) and 37 patients (43.53%) were normal (Group 2). The incidence of patients diagnosed with PRES was found to be 17.51% when all PE and eclampsia patients were included. International Normalized Ratio (INR), and prothrombin time (PTT) values were significantly higher, and maternal age, gravida, parity, platelet (PLT), and albumin values were significantly lower in the PRES group compared to the cases in group 2 (p<0.05). As a predictor of PRES, INR values higher than 0.94 (sensitivity=75.0%, specificity=67.6%) and PTT values higher than 11.7 (sensitivity=75.0%, specificity=54.1%) were found to be significant factors. Conclusion: We consider that high INR, PTT, low PLT, low albumin, young age, early gestational week, low gravida, and parity parameters can help clinicians to predict and diagnose earlier PRES cases due to obstetric causes.eninfo:eu-repo/semantics/openAccessEclampsiaHypertensionPreeclampsiaPresArticle3131781852-s2.0-8518901796010.59215/prn.23.0313001Q4