Fındık, Bahar TubaYıldız, HilalBirişçi, EsmaYiğitkan, SerkanYılmaz, Pelin KöseoğluErtaş, Abdulselam2025-02-222025-02-2220241300-30701309-6273https://doi.org/10.15237/gida.GD24028https://search.trdizin.gov.tr/tr/yayin/detay/1244984https://hdl.handle.net/11468/30207Herein, the angiotensin I-converting enzyme (ACE) inhibitory activity, antioxidant capacity, total polyphenol contents (TPC), and phytochemical profiles of polar and non-polar extracts of dried Ziziphus jujuba fruits were investigated, along with the statistical determination of the main components responsible for ACE inhibitory activity. The non-polar extract expressed the strongest ACE inhibitory activity (99.81%) among the extracts. The non-polar extract also exhibited the highest DPPH scavenging activity (IC50 of 30.63), linoleic acid/β-carotene bleaching capacity (89.31%), and TPC (59.47 mg GAE/g). The phenolic profiles of the extracts were identified by LC-MS/MS, and the presence of seven triterpenoid species in the extracts was examined using GC-MS techniques. The principal constituents included 19 phenolics, 2 organic acids, and 4 triterpenoids. A Pearson correlation and principal component analysis were conducted to find the correlation between individual phenolic compounds and ACE inhibitory activity.eninfo:eu-repo/semantics/openAccessZiziphus jujubaprincipal component analysisantioxidant capacityPearson correlationACE inhibitory activityphytochemical profileAN INVESTIGATION OF THE ACE INHIBITORY ACTIVITY, ANTIOXIDANT CAPACITY, AND PHYTOCHEMICAL CONSTITUENTS OF POLAR AND NON-POLAR EXTRACTS OF ZIZIPHUS JUJUBA FRUIT: STATISTICAL SCREENING THE MAIN COMPONENTS RESPONSIBLE FOR BIOACTIVITYArticle493554566124498410.15237/gida.GD24028