Ibrahim, Mahdi HashimSurchi, Badr QaderAzeez, Safiya A.Alma, M. HakkıKireçci, EkremYılmaz, Mustafa AbdullahUğuz, Metin Tansu2025-02-212025-02-212024Ibrahim, M. H., Surchi, B. Q., Azeez, S. A., Alma, M. H., Kireçci, E., Yılmaz, M. A. ve diğerleri. (2024). The anti-candidal activity of salvia verticillata subsp. verticillata against several candida species. Zanco Journal of Pure and Applied Sciences, 36(5), 12-23.2218-0230https://zancojournal.su.edu.krd/index.php/JPAS/article/view/1643/1206https://hdl.handle.net/11468/29480The examination of Salvia verticillata extract encompassed an exploration of its anti-Candida properties, phytochemical composition, antioxidant activity, and the quantification of total tannins. The use of ethanol as a solvent yielded the highest extraction efficiency at 26.1%. The plant exhibited a substantial tannin content of 6.5 mg/kg, signifying a noteworthy concentration. The inhibitory zones against Candida tropicalis reached a minimum diameter of 17.6 mm, while Candida guilliermondii displayed the most significant inhibition with a zone diameter of 21.8 mm. The minor inhibitory concentration (MIC) findings for all Candida species ranged from 6.25 to 12.5 g/ml. In the case of Candida guilliermondii, the synthetic antifungal activity FLU/25 demonstrated a maximal inhibition zone measuring 39.30 mm. Additionally, the maximum antioxidant activity, recorded at 0.3 ml, reached a value of 98.65. Phytochemical screening unveiled elevated concentrations of phenols and flavonoids, with malic acid (1901.1 g/g), hesperidin (302.4 g/g), and rosmarinic acid (30619.93 g/g) all experiencing an increase in concentration. These findings provide a comprehensive understanding of the diverse bioactive components and properties associated with Salvia verticillata extract.eninfo:eu-repo/semantics/closedAccessAnti-candida propertiesAntioxidant activityPhytochemical screeningSalvia verticillata extractTotal tannin quantificationArticle36512232-s2.0-85209915814N/A