Tatli, MehmetKeklikci, UgurAluclu, UfukAkdeniz, Sedat2024-04-242024-04-2420060014-30221421-9913https://doi.org/10.1159/000096180https://hdl.handle.net/11468/17949Anesthesia dolorosa (AD) is an uncommon complication of surgical treatments for trigeminal neuralgia. Its incidence is around 0.8%. To our best knowledge, AD caused by a penetrating cranial injury has not been reported previously. We report the case of a 31-year-old male patient with left-sided neuropathic keratitis and AD that began 18 years earlier, following a penetrating cranial injury with a knife to the left postauricular area. The patient was successfully treated by a carbamazepine and gabapentin combination. In conclusion, penetrating cranial injury is uncommon but may cause a serious neurologic disturbance. In the differential diagnosis of AD, a penetrating injury should be kept in mind. In these cases, treatments should be effective and immediate; otherwise, this may result in catastrophic consequences such as neurotrophic keratitis and blindness. Ophthalmologists should be aware of these potential problems. Copyright (c) 2006 S. Karger AG, Basel.eninfo:eu-repo/semantics/closedAccessAnesthesia DolorosaAnesthesia Dolorosa, MechanismPenetrating Cranial InjuryAnesthesia Dolorosa, TreatmentArticle563162165WOS:0002416157000032-s2.0-337511682691703570410.1159/000096180Q2Q4