Orak, M.Ustundag, M.Guloglu, C.Alyan, O.Sayhan, M. B.2024-04-242024-04-2420100300-0605https://doi.org/10.1177/147323001003800523https://hdl.handle.net/11468/18158This study investigated D-dimer levels in 241 patients admitted to the emergency department with sudden-onset chest pain. The patient group included those diagnosed with acute coronary syndrome (ACS; i.e. unstable angina pectoris [USAP], non-ST elevated myocardial infarction [NSTEMI], ST-elevated myocardial infarction [STEMI]); the control group included those diagnosed with non-cardiac chest pain. Mean serum levels of D-dimer, creatine kinase-MB (CK-MB) and troponin I (TPI) were compared between the groups. Levels of D-dimer, CK-MB and TPI in the patient group were significantly higher than in the control group. There were also significantly higher D-dimer, CK-MB and TPI levels in the STEMI and NSTEMI patient subgroups compared with the control group. Only the D-dimer level was significantly higher in the USAP subgroup versus the control group. The sensitivity and specificity of D-dimer for ACS were 83.7% and 95.4%, respectively, suggesting that evaluating D-dimer levels might be useful in the emergency room for diagnosing ACS and predicting mortality in patients presenting with acute chest pain.eninfo:eu-repo/semantics/closedAccessAcute Coronary SyndromeAngina PectorisMyocardial InfarctionChest PainD-DimerEmergency DepartmentDiagnosisMortalityArticle38517721779WOS:0002854040000232-s2.0-784492915022130949210.1177/147323001003800523Q2Q4