Saccone, GabrieleSen, CihatDi Mascio, DanieleGalindo, AlbertoGrunebaum, AmosYoshimatsu, JunStanojevic, MilanKurjak, AsimChervenak, FrankRodriguez Suarez, Maria JoseMaria Gambacorti-Passerini, ZitaAnaya Baz, Maria de los AngelesAguilar Galan, Esther VanessaCunarro Lopez, YolandaDe Leon Luis, Juan AntonioCueto Hernandez, IgnacioHerraiz, IgnacioVillalain, CeciliaVenturella, RobertaRizzo, GiuseppeMappa, IleniaGerosolima, GiovanniHellmeyer, LarsKoenigbauer, JosefineAmeli, GiadaFrusca, TizianaVolpe, NicolaLuca Schera, Giovanni BattistaFieni, StefaniaEsposito, EutaliaSimonazzi, GiulianaDi Donna, GaetanaYoussef, AlyDella Gatta, Anna NunziaDi Donna, Mariano CatelloChiantera, VitoBuono, NatalinaSozzi, GiulioGreco, PantaleoMorano, DanilaBianchi, BeatriceMarino, Maria Giulia LombanaLaraud, FedericaRamone, AriannaCagnacci, AngeloBarra, FabioGustavino, ClaudioFerrero, SimoneGhezzi, FabioCromi, AntonellaLagana, Antonio SimoneLongo, Valentina LauritaStollagli, FrancescaSirico, AngeloLanzone, AntonioDriul, LorenzaCecchini, FabianaXodo, SerenaRodriguez, BrianMercado-Olivares, FelipeElkafrawi, DeenaSisti, GiovanniEsposito, RosannaCoviello, AntonioCerbone, MarcoMorlando, MaddalenaSchiattarella, AntonioColacurci, NicolaDe Franciscis, PasqualeCataneo, IlariaLenzi, MarinellaSandri, FabrizioBuscemi, RiccardoGattei, Giorgiadella Sala, FrancescaValori, EleonoraRovellotti, Maria CristinaDone, ElisaFaron, GillesGucciardo, LeonardoEsposito, ValentinaVena, FlaminiaGiancotti, AntonellaBrunelli, RobertoMuzii, LudovicoNappi, LuigiSorrentino, FeliceLiberati, MarcoBuca, DaniloLeombroni, MartinaDi Sebastiano, FrancescaFranchi, MassimoIanniciello, Quintino CesareGarzon, SimonePetriglia, GiulianoBorrello, LeonardoNieto-Calvache, Albaro JoseBurgos-Luna, Juan ManuelKadji, CarolineCarlin, AndrewBevilacqua, ElisaMoucho, MarinaPinto, Pedro VianaFigueiredo, RitaMorales Rosello, JoseLoscalzo, GabrielaMartinez-Varea, AliciaDiago, VincenteJimenez Lopez, Jesus S.Aykanat, YelizCosma, StefanoCarosso, AndreaBenedetto, ChiaraBermejo, AmandaMay Feuerschuette, Otto HenriqueUyaniklar, OzlemOcakouglu, Sakine RahimliAtak, ZelihaGündüz, ReyhanHaberal, Esra TustasFroessler, BerndParange, AnupamPalm, PeterSamardjiski, IgorTaccaliti, ChiaraOkuyan, ErhanDaskalakis, GeorgeMoreira de Sa, Renato AugustoPittaro, AlejandroGonzalez-Duran, Maria LuisaConcheiro Guisan, AnaGenc, Serife OzlemZlatohlavkova, BlankaLuengo Piqueras, AnnaEsteban Oliva, DoloresCil, Aylin PelinApi, OlusAntsaklis, PanosPles, LianaKyvernitakis, IoannisMaul, HolgerMalan, MarcelLila, AlbertGranese, RobertaErcoli, AlfredoZoccali, GiuseppeVillasco, AndreaBiglia, NicolettaMadalina, CiuhodaruCosta, ElenaDaelemans, CarolinePintiaux, AxelleCueto, ElisaHadar, EranDollinger, SarahBrzezinski-Sinai, Noa A.Huertas, ErasmoArango, PedroSanchez, AmadeoAlfonso Schvartzman, JavierCojocaru, LiviuTuran, SifaTuran, OzhanDi Dedda, Maria CarmelaMolpeceres, Rebeca GarroteZdjelar, SnezanaPremru-Srsen, TanjaKornhauser-Cerar, LilijanaDruskovic, MiriamDe Robertis, ValentinaStefanovic, VedranNupponen, IrmeliNelskyla, KaisaKhodjaeva, ZulfiyaGorina, Ksenia A.Sukhikh, Gennady T.Maruotti, Giuseppe MariaVisentin, SilviaCosmi, ErichFerrari, JacopoGatti, AlessandraLuvero, DanielaAngioli, RobertoPuri, LudovicaPalumbo, MarcoD'Urso, GiusellaColaleo, FrancescoRapisarda, Agnese Maria ChiaraCarbone, Ilma FlorianaManzoli, LambertoFlacco, Maria ElenaNazzaro, GiovanniLocci, MariavittoriaGuida, MaurizioSardo, Attilio Di SpiezioPanici, Pierluigi BenedettiKhalil, AsmaBerghella, VincenzoBifulco, GiuseppeScambia, GiovanniZullo, FulvioD'Antonio, Francesco2021-04-092021-04-092021Saccone, G., Sen, C., Di Mascio, D., Galindo, A., Grunebaum, A., Yoshimatsu, J. ve diğerleri. (2021). Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection. Ultrasound in Obstetrics & Gynecology, 57(2), 232-2410960-76921469-0705https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.23107https://pubmed.ncbi.nlm.nih.gov/32926494/https://hdl.handle.net/11468/6640WOS:000613461600006PubMed ID: 32926494Objectives To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection. Methods This was a multinational retrospective cohort study including women with a singleton pregnancy and laboratory-confirmed SARS-CoV-2 infection, conducted in 72 centers in 22 different countries in Europe, the USA, South America, Asia and Australia, between 1 February 2020 and 30 April 2020. Confirmed SARS-CoV-2 infection was defined as a positive result on real-time reverse-transcription polymerase chain reaction (RT-PCR) assay of nasopharyngeal swab specimens. The primary outcome was a composite measure of maternal mortality and morbidity, including admission to the intensive care unit (ICU), use of mechanical ventilation and death. Results In total, 388 women with a singleton pregnancy tested positive for SARS-CoV-2 on RT-PCR of a nasopharyngeal swab and were included in the study. Composite adverse maternal outcome was observed in 47/388 (12.1%) women; 43 (11.1%) women were admitted to the ICU, 36 (9.3%) required mechanical ventilation and three (0.8%) died. Of the 388 women included in the study, 122 (31.4%) were still pregnant at the time of data analysis. Among the other 266 women, six (19.4% of the 31 women with first-trimester infection) had miscarriage, three (1.1%) had termination of pregnancy, six (2.3%) had stillbirth and 251 (94.4%) delivered a liveborn infant. The rate of preterm birth before 37 weeks' gestation was 26.3% (70/266). Of the 251 liveborn infants, 69/251(27.5%) were admitted to the neonatal ICU, and there were five (2.0%) neonatal deaths. The overall rate of perinatal death was 4.1% (11/266). Only one (1/251, 0.4%) infant, born to a mother who tested positive during the third trimester, was found to be positive for SARS-CoV-2 on RT-PCR. Conclusions SARS-CoV-2 infection in pregnant women is associated with a 0.8% rate of maternal mortality, but an 11.1% rate of admission to the ICU. The risk of vertical transmission seems to be negligible. (C) 2020 International Society of Ultrasound in Obstetrics and Gynecology.eninfo:eu-repo/semantics/openAccessCOVID-19SARS-CoV-2CoronavirusInfectionPregnancyArticle572232241WOS:0006093535000012-s2.0-851001119283292649410.1002/uog.23107Q1Q1