Bakır, Elif PınarYıldırım, Zehra SusgunBakır, ŞeyhmusKetani, Aydın2023-03-272023-03-272022Bakır, E.P., Yıldırım, Z.S., Bakır, Ş. ve Ketani, A. (2022). Are resin-containing pulp capping materials as reliable as traditional ones in terms of local and systemic biological effects? Dental Materials Journal, 41(1), 78-86.0287-4547https://www.jstage.jst.go.jp/article/dmj/41/1/41_2021-065/_articlehttps://hdl.handle.net/11468/11523The aim of this study was to compare the local and systemic effects of current pulp capping materials containing resin with those of traditional materials in an animal study. A total of 48 rats were used: a control group (n=12) (sub-control and negative control), a resin-containing group (n=18) (Calcimol LC, Theracal LC, Activa-BioActive Base/Liner), and a traditional group (n=18) (Biodentine, ProRoot MTA, Dycal). The materials which had been placed in polyethylene tubes were implanted in subcutaneous pockets. The rats were sacrificed at 1, 2, or 4 weeks. Evaluations were made of subcutaneous connective tissue, the left kidney, liver, and blood samples. Of all the study groups, MTA demonstrated biocompatibility at a level close to that of the control groups. Inflammation was observed to be more severe in resin-containing materials, but Activa Base/Liner showed a more successful local and systemic tissue response.eninfo:eu-repo/semantics/openAccessPulp cappingResin-containing materialsBiological effectsAnimal studyArticle4117886WOS:0007739978000102-s2.0-851240551093448320110.4012/dmj.2021-065Q1Q3