Ilhan, FulyaKalkanli, Sevgi Tas2024-04-242024-04-2420152307-8960https://doi.org/10.12998/wjcc.v3.i4.345https://hdl.handle.net/11468/18402Atherosclerosis is a chronic inflammatory disease arising from lipids, specifically low-density lipoproteins, and leukocytes. Following the activation of endothelium with the expression of adhesion molecules and monocytes, inflammatory cytokines from macrophages, and plasmacytoid dendritic cells, high levels of interferon (IFN)-alpha and beta are generated upon the activation of toll-like receptor-9, and T-cells, especially the ones with Th1 profile, produce pro-inflammatory mediators such as IFN-gamma and upregulate macrophages to adhere to the endothelium and migrate into the intima. This review presents an exhaustive account for the role of immune cells in the atherosclerosis.eninfo:eu-repo/semantics/openAccessAtherosclerosisInflammatory CytokinesPro-Inflammatory MediatorsImmune CellsAdhesion MoleculesReview Article34345352WOS:0004172366000032587900610.12998/wjcc.v3.i4.345N/A