Aydogan, TimucinUlas, TurgaySelcoki, YusufAlkan, RabiaYilmaz, Omer CaglarYalcin, Kadir SerkanInan, Osman2024-04-242024-04-2420120043-53251613-7671https://doi.org/10.1007/s00508-012-0150-0https://hdl.handle.net/11468/14489Background Helicobacter pylori ( H. pylori) is one of the most common bacterial infections, seen in humans worldwide and its possible relationship to different diseases is a focus of attention nowadays. The aim of this study was to analyse the effects of eradication on proteinuria. Ninety-nine patients suffering from dyspeptic complaints were recruited in this prospective study. The patients were divided into two groups according to the presence of infection. Thus, a total of 67 positive and 32 negative patients were studied. The positive patients' group was divided into two groups according to response to eradication treatment. A total of three groups were formed, viz; group 1 comprises of patients who are positive and responds positively to eradication therapy, group 2 comprises of patients who are positive and responds negatively to eradication therapy and group 3 is the control group and comprises of patients that are negative. Urine samples to obtain the protein/creatinine ratio were collected initially and at the end of the study from all patients. Mean difference levels (pre- and post-treatment difference) of urine protein/creatinine ratio was 0.055 +/- 0.13 in group 1. The ratio was -aEuro parts per thousand 0.0007 +/- 0.0067 in group 2 and -aEuro parts per thousand 0.0022 +/- 0.008 in group 3. A statistically significant difference was found in group 1 compared to the other groups in terms of mean difference levels of protein/creatinine ratios (p < 0.001). As a result of our study, treatment of eradication significantly reduced the proteinuria within the normal limits.eninfo:eu-repo/semantics/closedAccessInfectionsHelicobacter PyloriImmune ResponseTreatmentProteinuriaArticle1247-8241244WOS:0003041200000032-s2.0-848637228882252781310.1007/s00508-012-0150-0Q1Q3