Polat, NihatYildiz, AbdulkadirYuksel, MuratBilik, Mehmet ZihniAydin, MesutAcet, HalitAkil, Mehmet Ata2024-04-242024-04-2420141076-02961938-2723https://doi.org/10.1177/1076029613514131https://hdl.handle.net/11468/18119The aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil-lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS (P = .002) while lymphocyte count was lower (P = .034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.eninfo:eu-repo/semantics/openAccessRheumatic Valve DiseaseMitral StenosisNeutrophil To Lymphocyte RatioInflammationArticle208793798WOS:0003437757000052-s2.0-849210322562433524510.1177/1076029613514131Q2Q3