Avci A.Ülkü R.Onat S.2024-04-242024-04-2420091309-100Xhttps://hdl.handle.net/11468/24666Trisomy 21 or Down syndrome (DS) is the most common chromosome aberration in the newborn. Its high incidence has led to better understanding of congeniatal anomalies and diseases in association with this syndrome. The presence of protein, triglycerides, and lymphocytes in the pleural effusion is diagnostic of chylothorax. Lymph vessel abnormalities or a leaky thoracic duct are thought to be origin of congenital chylothorax, which is repoted many times in the literature. But, there is no information in the english literature about 1-year-old baby with DS who is complicated with chylothorax. Aplasia of the twelfth rib is rare but found to be more common in DS than in normals. We report on a 1-year-old girl with DS refered to our clinic with signs and symptoms of respiratory distress. Diagnosis and treatment of chylothorax, pleural emphyema, and pericardial effusion were obtained in algorithm.eninfo:eu-repo/semantics/closedAccessChylothoraxDown SyndromeArticle2125272-s2.0-80051590725Q3