Bilge, HuseyinBasol, Omer2024-04-242024-04-2420220025-79741536-5964https://doi.org/10.1097/MD.0000000000029582https://hdl.handle.net/11468/17308Background: The aim of our study was to investigate the prognostic role of platelet/albumin ratio in patients treated under emergency conditions for peptic ulcer perforation (PUP). Methods: A retrospective study involving emergency patients who were operated for PUP was carried out. The patients were divided into 2 groups: PUP patients who died after surgical treatment (PUP-M) and PUP patients who survived after surgical treatment (PUP-S). The laboratory values of the patients were compared statistically. A P value of Results: This cohort study consisted of 171 patients treated between June 2013 and December 2019. The mean age of the patients was 46.3 +/- 20.5 years; and 33 (19.3%) patients were women. The age (P <= .001), platelet/lymphocyte ratio (P = .02), lactic dehydrogenase to albumin ratio (P <= .001), and platelet/albumin ratio (PAR; P <= .001) values were high and lymphocyte count was low (P = .006) in the PUP-M group. A positive correlation was determined between length of stay in hospital and age (P <= .001), lactic dehydrogenase/albumin ratio (P <= .001), platelet count (P = .044), and PAR (P <= .001). A substantial negative correlation was determined between length of stay in hospital and albumin count (P <= .001). Conclusions: We determined a high preoperative PAR level in PUP patients who had undergone surgery as a negative prognostic parameter. PAR is a candidate biomarker for clinical practice.eninfo:eu-repo/semantics/openAccessHospital MortalityPeptic Ulcer PerforationSerum AlbuminArticle10131WOS:0008377775000682-s2.0-851357338393594580210.1097/MD.0000000000029582Q2Q3