Şenol, EsinÇilli, AykutGünen, HakanŞener, AlperDumlu, RıdvanÖdemiş, AyşeTopçu, Ayşe Füsun2024-02-272024-02-272021Şenol, E., Çilli, A., Günen, H., Şener, A., Dumlu, R., Ödemiş, A. ve diğerleri. (2021). The role of pneumococcal pneumonia among community-acquired pneumonia in adult turkish population: Turkcap study. Turkish Thoracic Journal, 22(4), 339-345.2149-2530https://thoracrespract.org/en/the-role-of-pneumococcal-pneumonia-among-community-acquired-pneumonia-in-adult-turkish-population-turkcap-study-131778%5Chttps://hdl.handle.net/11468/13401https://search.trdizin.gov.tr/yayin/detay/457799OBJECTIVE: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients. MATERIAL AND METHODS: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age ≥ 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia. RESULTS: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P =.007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P =.235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P =.002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group. CONCLUSION: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.eninfo:eu-repo/semantics/openAccessAdultCommunity-acquired pneumoniaStreptococcus pneumoniaeArticle224339345WOS:0006726408000112-s2.0-851093299804577993511025210.5152/TurkThoracJ.2021.20223Q4N/A