Ak, BunyaminAydemir, MuratDurap, FeyyazMeric, NerminElma, DuyguBaysal, Alan2024-04-242024-04-2420150957-4166https://doi.org/10.1016/j.tetasy.2015.10.002https://hdl.handle.net/11468/16113A series of chiral modular C-2-symmetric ferrocenyl phosphinite ligands have been synthesized in good yields by using 1,1'-ferrocenedicarboxyaldehyde and various amino alcohols as starting materials, and applied in the iridium(III)-catalyzed asymmetric transfer hydrogenations of aromatic ketones to give the corresponding secondary alcohols with good enantioselectivities and reactivities using 2-propanol as the hydrogen source (up to 98% ee and 99% conversion). The substituents on the backbone of the ligands were found to have a significant effect on both the activity and enantiomeric excess. The structures of these complexes have been clarified by a combination of multinuclear NMR spectroscopy, IR spectroscopy, and elemental analysis. (C) 2015 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccess[No Keyword]Highly efficient iridium catalysts based on C2-symmetric ferrocenyl phosphinite ligands for asymmetric transfer hydrogenations of aromatic ketonesHighly efficient iridium catalysts based on C2-symmetric ferrocenyl phosphinite ligands for asymmetric transfer hydrogenations of aromatic ketonesArticle262313071313WOS:0003660700000012-s2.0-8494744052110.1016/j.tetasy.2015.10.002N/AQ2