Temel, HamdiUçmak, HasanPaşa, SalihYılmaz, Mustafa A.Hoşoğlu, Salih2025-03-082025-03-0820132146-46932458-9330https://hdl.handle.net/11468/30634The Schiff base ligands N,N -bis salicylidene -1,2-bis- o-aminophenoxy ethane L1 and N,N -bis salicylidene 1,2-bis- p-aminophenoxy ethane L2 were synthesized for this study. The Cu II , Ni II , Zn II complexesof L1 and the Cu II , Co II , Zn II complexes of L2 were obtained with various transition metal salts.These compounds were evaluated against to the common infectious bacteria in human such as E. coli,Pseudomonas, Acinetobacter and Staphylococcus strains. The copper complexes of both L1 and L2 were foundeffective against Staphylococcus strains. Staphylococcus strains are common pathogens in hospital environment.Thus, their copper complexes L1-Cu and L2-Cu may be useful in hospital hygieneBu çal›flma için N,N -bis(salisiliden)-1,2-bis-(o-aminofenoksi)etan (L1) ve N,N -bis(salisiliden)-1,2-bis-(paminofenoksi)etan (L2) Schiff bazlar› sentezlendi. Bu ligandlardan da L1’in Cu(II), Ni(II), Zn(II) kompleksleri, L2’nin Cu(II), Co(II), Zn(II) kompleksleri elde edildi. Sentez sonras› elde edilen bu bileflikler, insanlarda yayg›n olarak görülen bulafl›c› bakteriler E. coli, Pseudomonas, Acinetobacter ve Staphylococcus’a karfl› etkinlikleri incelenmifltir. Her iki ligand›n da bak›r kompleksleri Staphylococcus’a karfl› etkili oldu¤u bulunmufltur. Staphylococcus, hastane çevresinde yayg›n olarak görülen patojenlerdendir. Bu yüzden bu ligandlar›n bak›r kompleksleri (L1-Cu ve L2-Cu) hastane hijyeninde kullan›fll› olabilece¤i düflünülmektedir.eninfo:eu-repo/semantics/openAccessTransition metal complexAntimicrobial activitytransition metalsalisilidenaminofenoksimetal komplekslerArticle211619