Turhanoglu S.Ozyilmaz M.A.Cinar F.S.Tok D.Olmez G.Bayhan N.2024-04-242024-04-2419991016-5150https://hdl.handle.net/11468/24118Sixty ASA class I or II patients were included to the study in which the effects of magnesium sulphate and alfentanil combination on the haemodynamic response to tracheal intubation and intraoperative haemodynamic control had been investigated. The patients were randomly allocated into three groups. At the induction of anaesthesia, the patients of group I (n=20) were received isotonic sodium chloride IV bolus and infusion, and 10 ?g/kg alfentanil, group II (n=20) were received IV magnesium sulphate 20 mg/kg bolus and 10 mg/kg/h infusion, and group III (n=20) were received IV magnesium sulphate 20 mg/kg bolus with 10 mg/kg/h infusion and 10 ?g/kg alfentanil. Anaesthesia induction and maintenance were performed respectively with thiopentone 5 mg/kg, isoflurane (% 1-1,5) in 50 % nitrous oxide and 50 % oxygen in all groups. Magnesium and alfentanil combination produced better control of arterial pressure and heart rate than magnesium and alfentanil alone (p<0.05). Furthermore, the consumption of alfentanil during the surgery were found significantly higher in group I than groups II and III (p<0.05). In conclusion we considered that the doses of magnesium sulphate and alfentanil combination in this study were adequate to attenuate the haemodynamic response to tracheal intubation and produce better control of arterial pressure and heart rate.trinfo:eu-repo/semantics/closedAccessAlfentanilHaemodynamic Response To Tracheal İntubationIntraoperative Control Of HaemodynamicsMagnesium SulphateArticle2795035072-s2.0-0033377063N/A