Chiral separation of amino acids using a chiral crown ether by impregnation on a polymeric support and monoamine modified silica gel

Seyhan, SerapTurgut, YilmazMerdivan, MelekHosgoren, Halil2024-04-242024-04-2420060957-4166https://doi.org/10.1016/j.tetasy.2006.06.008https://hdl.handle.net/11468/16099A chiral monoaza-15-crown-5 ether derivative was prepared from L-Leucinol and used as a chiral stationary phase. The new chiral stationary phases CSP-1 and CSP-2 were employed in separating the enantiomers of the sodium and potassium salts of amino acids. The sodium and potassium salt of the D-enantiomers of all amino acids (PhyAlaNa, PhyAlaK and PhyGlyNa, PhyGlyK, and TrpNa, TrpK) show higher selectivity than the L-enantiomers for both CSP-1 and CSP-2. (c) 2006 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccess[No Keyword]Chiral separation of amino acids using a chiral crown ether by impregnation on a polymeric support and monoamine modified silica gelChiral separation of amino acids using a chiral crown ether by impregnation on a polymeric support and monoamine modified silica gelArticle171117001704WOS:0002395227000162-s2.0-3374585549110.1016/j.tetasy.2006.06.008N/AQ2