Hazar, LeylaOyur, GülistanYılmaz, Gülay CanVural, Esra2022-05-302022-05-302021Hazar, L., Oyur, G., Yılmaz, G.C. ve Vural, E (2021). Relationship of obesity and related disorders with ocular parameters in children and adolescent. Current Eye Reserach, 46(9), 1393-1397.0271-36831460-2202https://www.tandfonline.com/doi/full/10.1080/02713683.2021.1884727https://hdl.handle.net/11468/9915WOS:000618248500001PMID: 33586562PURPOSE To evaluate the effect of obesity and obesity-related high blood pressure (BP) on the retinal nerve fiber layer (RNFL) and macula in children and adolescents. MATERIALS AND METHODS Thirty-two obese patients followed up in the pediatrics endocrinology clinic between 2018 and 2019 were evaluated in the ophthalmology clinic. The results were compared with 25 healthy subjects, matched for age and sex. Anthropometric measurements, and systolic and diastolic BP were measured. The study consisted of three groups: Group 1, patients with obesity; Group 2, those with obesity and associated hypertension (obesity-related HT); and Group 3, healthy controls. A complete ophthalmologic examination was performed. Macular and RNFL thicknesses were determined using spectral domain optical coherence tomography (SD-OCT). RESULTS There were no statistically significant differences between the groups in terms of gender, age, and intraocular pressure (p > .05). The inferior RNFL thickness and central foveal thickness were statistically thinner in the obesity-related HT group (p < .001 and p = .040). The systolic and diastolic BP and fasting glucose values were significantly higher in the obesity-related HT group than the other groups (p < .001; p < .001; p = .026, respectively). In linear regression modeling in obese and obesity-related HT groups, a significant assocation was found between diastolic BP and temporal RNFL thickness (p = .027) as well as between the systolic BP and triglyceride values and the nasal RNFL thickness values (p = .016 and p = .025, respectively). CONCLUSIONS Inferior RNFL thickness and central foveal thickness were significantly thinner in patients with obesity-related HT. The effects of obesity-related HT on the retina should be evaluated using SD OCT, since no signs were found in a routine ocular examination.eninfo:eu-repo/semantics/closedAccessChildhood obesityBlood pressureRetina nerve fiberOptic coherence tomographyIntraocular pressureArticle46913931397WOS:0006182485000012-s2.0-851009488433358656210.1080/02713683.2021.1884727Q1Q3