Okur, Mehmet HanifiAydoğdu, BahattinArslan, Mehmet ŞerifAlabalık, UlaşArslan, SerkanKara, İbrahimCanpolat, FethiyeŞahin, AtalayOtçu, Selçuk2023-10-272023-10-272014Okur, M. H., Aydoğdu, B., Arslan, M. Ş., Alabalık, U., Arslan, S., Kara, İ. ve diğerleri. (2014). Intra-peritoneal administration of Ecballium elaterium diminishes postoperative adhesions. Acta Cirurgica Brasileira, 29(10), 639-643.0102-8650https://www.scielo.br/j/acb/a/kjZtMf3F8tKRZyqnPLchhmQ/?lang=enhttps://hdl.handle.net/11468/12983RESULTS: The adhesion score was significantly decreased in the EE group (p=0.001) in comparison with the control group. Microscopically, the EE and sham groups were significantly lower than that of the control group (p[removed] METHODS: Thirty rats were divided into three groups and underwent midline laparotomy under 35 mg/kg ketamine and 5 mg/kg xylazine anaesthesia. In group 1 (n=10), the sham operation group, the abdominal walls were closed without any process. In group 2 (n=10), the control group, the antimesenteric border of the ceacum and the corresponding parietal peritoneum were abraded with dry sterile gauze. In group 3 (n=10), the EE group, 2.5 mg/kg dose of EE was administered as intraperitoneally to the rats after abrasion. All rats were sacrificed on postoperative day 15. Samples were obtained. CONCLUSION: The grade and severity of abdominal adhesion could be significantly reduced through administered Ecballium elaterium and therefore be a suitable anti-inflammatory agent for the prevention of postoperative peritoneal adhesion in the future. PURPOSE: To evaluate the effects of Ecballium elaterium (EE), Elaterium officinarum, in postoperative intraperitoneal adhesions in rats.eninfo:eu-repo/semantics/openAccessAdhesionAnti-inflammatory agentsElaterium officinarumPeritoneumRatsArticle2910639643WOS:0003439821000032-s2.0-849080723552531799510.1590/S0102-8650201400160003Q2Q4