Aygun, HusamettinKaramese, MuratOzic, CemUyar, Fikret2024-04-242024-04-2420181746-09131746-0921https://doi.org/10.2217/fmb-2017-0133https://hdl.handle.net/11468/18865Aim: Adherent-invasive Escherichia coli (AIEC) pathovar has been identified in intestinal mucosa of patients with Crohn's disease. Our aim was to compare the impact of sterile mucosal media (Muc-M) originated from different parts of the intestine on some pathogenic traits of AIEC LF82 strain. Materials & methods: Muc-M composed of certain rates of cell culture medium or M63 minimal medium and mucosal contents obtained from different part of intestine were designed for cell-infection experiments and biofilm-formation assays. Results: The results showed that Muc-M reduced usually pathogenic properties of AIEC LF82. However, LF82 adhesion, invasion and specific biofilm formations were markedly higher in Muc-MCR than those in Muc-MIR. Conclusion: In this context, the findings of present study could help the endeavors related to determining molecular targets for AIEC bacteria.eninfo:eu-repo/semantics/closedAccessAdhesionBiofilmCrohn's DiseaseEscherichia Coli Lf82InvasionPathobiontArticle132141149WOS:0004272735000022-s2.0-850490650532930299810.2217/fmb-2017-0133Q2Q3