Okur, Mehmet HanifiAydoǧdu, BahattinAzizoǧlu, MustafaBilici, SalimBayram, SalihSalık, Fikret2023-10-062023-10-062023Okur, M. H., Aydoğdu, B., Azizoğlu, M., Bilici, S., Bayram, S. ve Salık, F. (2023). Laparoscopic versus open portoenterostomy for treatment of biliary atresia: a meta‑analysis. Pediatric Surgery International, 39(1), 148.0179-0358https://link.springer.com/article/10.1007/s00383-023-05436-8https://hdl.handle.net/11468/12765Objective: Our goal was to compare laparoscopic portoenterostomy versus open portoenterostomy for the treatment of biliary atresia. Materials and methods: Using the databases EMBASE, PubMed, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing laparoscopic and open surgery for the treatment of biliary atresia were included. Results: Twenty-three studies comparing laparoscopic portoenterostomy (LPE) (n = 689) and open portoenterostomy (OPE) (n = 818) were considered appropriate for meta-analysis. Age at surgery time was lower in the LPE group than OPE group (I2 = 84%), (WMD − 4.70, 95% CI − 9.14 to − 0.26; P = 0.04). Significantly decreased blood loss (I2 = 94%), (WMD − 17.85, 95% CI − 23.67 to − 12.02; P < 0.00001) and time to feed were found in the laparoscopic group (I2 = 97%), (WMD − 2.88, 95% CI − 4.71 to − 1.04; P = 0.002). Significantly decreased operative time was found in the open group (I2 = 85%), (WMD 32.52, 95% CI 15.65–49.39; P = 0.0002). Weight, transfusion rate, overall complication rate, cholangitis, time to drain removal, length of stay, jaundice clearance, and two-year transplant-free survival were not significantly different across the groups. Conclusions: Laparoscopic portoenterostomy provides advantages regarding operative bleeding and the time to begin feeding. No differences in remain characteristics. Based on the data presented to us by this meta-analysis, LPE is not superior to OPE in terms of overall results.eninfo:eu-repo/semantics/closedAccessBiliary atresiaKasai portoenterostomyLaparoscopyOpenArticle391110WOS:0009453804000012-s2.0-851495038943688120110.1007/s00383-023-05436-8Q2N/A