Gürkan, FuatDavutoğlu, MehmetBoşnak, MehmetEce, AydınDikici, BünyaminBilici, MekiHaspolat, Yusuf Kenan2021-12-082021-12-082004Gürkan, F., Davutoğlu, M., Boşnak, M., Ece, A., Dikici, B., Bilici, M. ve diğerleri. (2004). Pamidronate treatment in acute vitamin D intoxication. Journal of Endocrinological Investigation, 27(7), 680-682.1720-8386https://hdl.handle.net/11468/8372Management with glucocorticoid, high iv fluid saline intake, furosemide and calcitonin may not result in a favorable reduction of hypercalcemia and may cause several side effects in infants with acute vitamin D intoxication. The bisphosphonate pamidronate, a specific inhibitor of bone resorption through osteoclast mediation was successfully used in a 6-month old infant with acute vitamin D intoxication managed in the Pediatric Emergency and Intensive Care Unit, after an ineffective trial of hydration, furosemide, calcitonin and prednisolone. After a double infusion of pamidronate on two consecutive days (1 mg/kg/day), an early and safe correction of hypercalcemia/hypercalciuria was supplied. Pamidronate therapy may be considered in patients with hypercalcemia secondary to acute vitamin D poisoning.eninfo:eu-repo/semantics/closedAccessAcutePamidronateVitamin D intoxicationArticle277680682WOS:0002241869000132-s2.0-54442544251550599410.1007/BF03347503Q1Q3