Turgut, YilmazAzizoglu, MuratErdogan, AsliArslan, NevinHosgoren, Halil2024-04-242024-04-2420130957-4166https://doi.org/10.1016/j.tetasy.2013.05.016https://hdl.handle.net/11468/16109In order to find the most effective catalyst for the enantioselective reduction of a prochiral ketone, a series of novel beta-hydroxyamide derivatives of salicylic acid and chiral amino alcohols were synthesized. Different substituted prochiral ketones have been reduced in high yield (up to 99%) and the corresponding secondary alcohols are formed with good enantiomeric excess (up to 86%). The mechanism of this type of catalyst can be explained by considering the reaction mechanism for the CBS catalyst. (C) 2013 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccess[No Keyword]Article2413-14853859WOS:0003226105000132-s2.0-8488031965010.1016/j.tetasy.2013.05.016N/AQ2