Altunkaynak, YalçınYavuz, ÖmerLevent, Abdulkadir2021-12-082021-12-082021Altunkaynak, Y., Yavuz, Ö. ve Levent, A. (2021). Firstly electrochemical examination of vildagliptin at disposable graphite sensor: Sensitive determination in drugs and human urine by square-wave voltammetry. Microchemical Journal, 170, 1-7.0026-265X1095-9149https://hdl.handle.net/11468/8363WOS:000713236500003The work describes the determination of vildagliptin at the pencil graphite electrode using cyclic voltammetry and square-wave voltammetry. Vildagliptin yielded a well-defined irreversible peak response in phosphate buffer (PBS 9.0) medium, at about +1.13 V by cyclic voltammetry. Using optimum square-wave voltammetry condi-tions, a good linear correlation was obtained between the anodic current signal and concentration, in the range of 2.94-49.98 mu M in PBS (pH 9.0) medium, the limit of detection and relative standard deviation were calculated as 82 nM (24.88 ng L-1) and 2.95%, respectively. The developed voltammetric method was successfully applied for vildagliptin determination without any separation in pharmaceutical preparations and urine samples.eninfo:eu-repo/semantics/closedAccessVildagliptinGraphite electrodeVoltammetryArticle17017WOS:0007132365000032-s2.0-8511101047710.1016/j.microc.2021.106653Q1Q1