Gurel, KamilGur, SerkanOzkan, UgurTekbas, GuvenOnder, HakanOguzkurt, Levent2024-04-242024-04-2420121305-3825https://doi.org/10.4261/1305-3825.DIR.4933-11.1https://hdl.handle.net/11468/19645PURPOSE This study retrospectively evaluated ultrasonography-guided (US-guided) percutaneous thrombin injection for the treatment of postcatheterization femoral and brachial artery pseudoaneurysms. MATERIALS AND METHODS Fifty-five patients with postcatheterization femoral artery (n=53) or brachial artery (n=2) pseudoaneurysms were treated using US-guided human thrombin (500 IU/mL) injection. Pseudoaneurysm size, thrombin dose, therapy outcome, and complications were documented. Follow-up color Doppler US was performed 7 and 30 days after treatment. Short-duration supplemental compression was applied to six patients at the first week follow-up examination after a reinjection of thrombin had failed. RESULTS Mean pseudoaneurysm volume was 20.3 +/- 18.7 cm(3). The mean injected thrombin dose was 478 +/- 238 IU. Thirty-eight (69.1%) of the 55 pseudoaneurysms were thrombosed with a single injection, and 11 of 17 pseudoaneurysms were thrombosed after a second injection. All (100%) of the 41 pseudoaneurysms that were diagnosed within the first two weeks of postcatheterization were successfully treated. The overall primary success rate was 89.1% (49 of 55 pseudoaneurysms). Supplemental compression promoted thrombosis in four of the six patients who had treatment failure with thrombin injection. The secondary success rate was 96.4% (53 of 55 pseudoaneurysms). There were no complications. CONCLUSION US-guided thrombin injection was most successful within the first two weeks, and the supplemental compression might aid in the closure of partially thrombosed pseudoaneurysms.eninfo:eu-repo/semantics/closedAccessPseudoaneurysmTherapeutic EmbolizationThrombinArticle183319325WOS:0003160610000132-s2.0-848615227072219891110.4261/1305-3825.DIR.4933-11.1Q2Q4