Kanay Z.Sert C.Isik B.Kurt D.Guzel C.Mete N.2024-04-242024-04-2419981300-4948https://hdl.handle.net/11468/24138We investigated the effect of glutathione (GSH) on the gastric mucosal barrier of rats under stress. Twenty two swiss Albino rats weighing between 150-200 g were used and stress was induced by cold and immobilisation. GSH was administered in 300 mg/kg doses to the study group and oral saline was given to a control group. Mucus and phospholipid levels of the gastric mucosal barrier were then measured using come and Baur's methods. These important components of the gastric mucosal barrier were found to be decreased (p<0.05), but levels were higher in rats given GSH than in the control group (p<0.01, p<0.05 respectively). To conclude, GSH was found to be effective in preventing gastric mucosal barrier damage caused by stress.trinfo:eu-repo/semantics/closedAccessGasric Mucosal BarrierGlutathioneStressArticle932262282-s2.0-0031665969N/A