Ozler, AliTurgut, AbdulkadirSoydinc, Hatice EnderSak, Muhammet ErdalEvsen, Mehmet SiddikAlabalik, UlasBasarali, Mustafa Kemal2024-04-242024-04-2420131933-71911933-7205https://doi.org/10.1177/1933719113485300https://hdl.handle.net/11468/18178Objective: The aim of the present study was to determine to what extent ovarian reserves are affected by ischemia-reperfusion injury, evaluating the number of growing follicles and the serum levels of the ovarian hormones. Study Design: Thirty female fertile adult Wistar albino rats, weighing 200 to 220 g, were previously numbered to randomization, and then randomly divided into 3 equal groups (n = 10): sham, torsion, and detorsion groups. In torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Results: The mean number of preantral and small antral follicles in detorsion group were lower than those of the sham group (P < .01). After torsion, anti-Mullerian hormone (AMH), estradiol, and inhibin B levels decreased significantly compared to the preoperative and postoperative periods (P = .003, P = .032, and P = .014, respectively). In detorsion group, only AMH levels were found to decrease significantly following the 3-hour ischemia and 3-hour reperfusion (P < .05). Conclusion: After adnexal torsion, a significant decrease in ovarian reserve has been detected for the first time in this study. Additionally, the results of this study suggest that conservative surgery alone is insufficient to protect ovarian reserve.eninfo:eu-repo/semantics/closedAccessAdnexal TorsionOvarian ReserveOvarian FolliclesAnti-Mullerian HormoneInhibin BArticle201113491355WOS:0003254779000112-s2.0-848856772132358534410.1177/1933719113485300Q1Q2