Hosoglu, SalihGeyik, Mehmet FarukAkalin, SerifeAyaz, CelalKokoglu, Omer FarukLoeb, Mark2024-04-242024-04-2420060035-9203https://doi.org/10.1016/j.trstmh.2005.12.007https://hdl.handle.net/11468/16157The goal of this study was to develop a simple prediction rule for the diagnosis of typhoid fever. A model for the prediction of patients with typhoid fever at hospital admission was derived and validated by assigning weighted point values to independent predictive factors associated with a diagnosis of typhoid fever at hospital admission. Patient demographic, clinical and laboratory variables were used to compare patients with blood culture-confirmed typhoid fever with patients with fever of unknown origin. The model was derived and validated in two separate cohorts of patients from Dicle University Hospital in Diyarbakir, Turkey. A total of 371 patients were enrolled. A diagnostic index score was created using seven independent predictive factors associated with typhoid fever at hospital admission: age <30 years, abdominal. distention, confusion, leukopenia, relative bradycardia, positive Widal test and a typhoid tongue. A clinical prediction rule helped to differentiate patients with typhoid fever. (C) 2006 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessTyphoid FeverEnteric FeverDiagnosisPrediction RuleTurkeyArticle1001110681074WOS:0002411182000112-s2.0-337481536361669743210.1016/j.trstmh.2005.12.007Q2Q2