Urun, YukselUtkan, GungorCangir, Ayten KayiOksuzoglu, Omur BernaOzdemir, NuriyeOztuna, Derya GokmenKocaman, Gokhan2024-04-242024-04-2420131513-7368https://doi.org/10.7314/APJCP.2013.14.5.2801https://hdl.handle.net/11468/20390Background: The ABO blood groups and Rh factor may affect the risk of lung cancer. Materials and Methods: We analyzed 2,044 lung cancer patients with serologically confirmed ABO/Rh blood group. A group of 3,022,883 healthy blood donors of Turkish Red Crescent was identified as a control group. We compared the distributions of ABO/Rh blood group between them. Results: The median age was 62 years (range: 17-90). There was a clear male predominance (84% vs. 16%). Overall distributions of ABO blood groups were significantly different between patients and controls (p=0.01). There were also significant differences between patients and controls with respect to Rh positive vs. Rh negative (p=0.04) and O vs. non-O (p=0.002). There were no statistically significant differences of blood groups with respect to sex, age, or histology. Conclusions: In the study population, ABO blood types were associated with the lung cancer. Having non-O blood type and Rh-negative feature increased the risk of lung cancer. However, further prospective studies are necessary to define the mechanisms by which ABO blood type may influence the lung cancer risk.eninfo:eu-repo/semantics/openAccessAbo BloodGroup SystemLung NeoplasmsCancerRisk FactorsArticle14528012803WOS:0003314734000192-s2.0-850476876582380303410.7314/APJCP.2013.14.5.2801Q3Q4