Faruk, E. R.Deveci, EnginKalkanlı, SevgiDeveci, Büşra2024-04-242024-04-242013Faruk, E. R., Deveci, E., Kalkanlı, S. ve Deveci, B. (2013). The effects of nicotine on the incisive teeth and expression of vimentin in rats. International Journal of Morphology, 31(2), 516-519.0717-9367https://doi.org/10.4067/S0717-95022013000200026https://hdl.handle.net/11468/23821Nicotine is an alkaloid toxic effects of oral cavity. In this study,14 adult Sprague-Dawley rats weighing 230-260 mg (±10 mg) were used as experimental animal. The rats of experimental group (n=6) were nicotinized systemically with nicotine sulphate, 2mg/kg subcutaneously, daily in period of 28 days. Pulp, alveolar bone tissue, periodontal membrane and gingival epithelial junction were investigated in these regions in incisive teeth longitudinal cross-section. Thinning of the collagen fibers in the pulp tissue, vascular congestion, and inflammatory cell infiltration were observed. Mesenchymal tissues that is stained positive for vimentin lay underneath the epithelium. A strong expression of vimentin can be observed in formed periodontal ligament.eninfo:eu-repo/semantics/openAccessNicotineRatVimentinArticle312516519WoSidYok2-s2.0-8488480478610.4067/S0717-95022013000200026Q3N/A