Karahan, MineErdem, SeyfettinHazar, LeylaDursun, Mehmet EminAva, SedatEmek, HüseyinKeklikçi, Uğur2022-06-132022-06-132021Karahan, M., Erdem, S., Hazar, L., Dursun, M.E., Ava, S., Emek, H. ve diğerleri. (2021). Bilateral central retinal artery occlusion secondary to SARS-CoV-2 infection in the early and late periods: A case report. Klinische Monatsblatter Für Augenheilkunde, 238(12), 1325-1327.0023-21651439-3999https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1353-5915https://hdl.handle.net/11468/9980WOS:000621544900009PMID: 33607682The causative agent of coronavirus disease (COVID-19) is a new virus termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the coronavirus family. It was first detected in China in December 2019 and spread rapidly around the world. COVID-19 is highly contagious and mainly transmitted through contact with infected patients or droplets. The most common symptoms are fever, cough, weakness, muscle pain, and shortness of breath [1]. SARS-CoV-2 infects host cells through the renin angiotensin-converting enzyme 2 (ACE2) receptors. The ACE2 receptor is widely expressed in many organs, including the retina, and plays a role in the pathogenesis of systemic vascular diseases, which can lead to ocular symptoms such as diabetic and hypertensive retinopathy [2], [3]. SARS-COV-2 has been reported to be associated with neurological symptoms, including stroke, thromboembolism (e.g., pulmonary embolism), and myocardial infarction. Hypercoagulation associated with COVID-19 has been described as “sepsis-induced coagulopathy” and may predispose patients to the spectrum of thromboembolic events [4], [5], [6]. We present here the first case of bilateral central retinal artery occlusion (CRAO) that developed in the early and late stages secondary to the SARS-CoV-2 infection.eninfo:eu-repo/semantics/closedAccessEditorial2381213251327WOS:0006215449000092-s2.0-851013430203360768210.1055/a-1353-5915Q3Q4